233276-30-7

Upstream product

• 124-73-2 1,2-dibromo-1,1,2,2-tetrafluoroethane 
• 233276-27-2 6-chloro-3-(2-fluorophenyl)-7-(trimethylsilyl)-[1,2,4]triazolo[4,3-b]pyridazine 
• 262422-89-9 benzoic acid N'-(6-chloro-5-trimethylsilanyl-pyridazin-3-yl)-hydrazide 
• 262422-90-2 6-chloro-3-phenyl-7-trimethylsilanyl-[1,2,4]triazolo[4,3-b]pyridazine 

Downstream Products

• 233276-31-8 7-Bromo-3-(2-fluorophenyl)-6-(2-methyl-2H-1,2,4-triazol-3-ylmethoxy)-1,2,4-triazolo [4,3-b]pyridazine 

Relevant academic research and scientific papers

Triazolo-pyridazine derivatives as ligands for GABA receptors

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing a fluoro-substituted phenyl ring at the 3-position and a heteroaryl-alkoxy moiety at the 6-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2

Rapid analogue synthesis of trisubstituted triazolo[4,3-b]pyridazines

A rapid analogue synthesis of biologically active 3,6,7-trisubstituted 1,2,4-triazolo[4,3-b]pyridazines was devised to give easy and selective variation of the three substituents through combinations of silicon-directed anion formation, palladium-catalysed couplings and S(N)Ar displacements. (C) 2000 Elsevier Science Ltd.