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Ethanone, 1-(4-methyl-1H-imidazol-5-yl)-, commonly known as ketoconazole, is an antifungal medication that exhibits potent antifungal activity by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to cell death and the elimination of fungal infections. Ketoconazole is recognized for its versatility in treating a range of fungal conditions and also possesses anti-androgenic properties, expanding its therapeutic applications.

23328-91-8

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23328-91-8 Usage

Uses

Used in Antifungal Treatments:
Ethanone, 1-(4-methyl-1H-imidazol-5-yl)is used as an antifungal agent for treating various fungal infections, such as athlete's foot, ringworm, and yeast infections. Its mechanism of action involves the disruption of ergosterol production, which is essential for maintaining the integrity of fungal cell membranes, thereby leading to cell death and infection resolution.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethanone, 1-(4-methyl-1H-imidazol-5-yl)is utilized as an active pharmaceutical ingredient in the development of antifungal medications. It is formulated into different dosage forms, including creams, shampoos, and oral tablets, to cater to the specific needs of patients and ensure effective treatment of fungal infections.
Used in Off-Label Treatments:
Ethanone, 1-(4-methyl-1H-imidazol-5-yl)is also used off-label for conditions such as hirsutism and alopecia, leveraging its anti-androgenic properties. This application takes advantage of its ability to inhibit the effects of androgens, which can contribute to the management of these conditions when used under the guidance of a healthcare professional.
Used in Research and Development:
In the field of research and development, Ethanone, 1-(4-methyl-1H-imidazol-5-yl)serves as a key compound for studying the mechanisms of antifungal action and exploring potential synergistic effects with other medications. This research can lead to the discovery of new therapeutic agents and treatment strategies for fungal infections and other related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 23328-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,3,2 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23328-91:
(7*2)+(6*3)+(5*3)+(4*2)+(3*8)+(2*9)+(1*1)=98
98 % 10 = 8
So 23328-91-8 is a valid CAS Registry Number.

23328-91-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(5-methyl-1H-imidazol-4-yl)ethanone

1.2 Other means of identification

Product number -
Other names 1-(5-methyl-1(3)H-imidazol-4-yl)-ethanone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23328-91-8 SDS

23328-91-8Relevant academic research and scientific papers

Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones

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, (2008/06/13)

This disclosure describes a novel process for the preparation of 1-(lower alkyl)substituted derivatives of 6-n-propyl-8-alkylimidazo[1,5-d]-as-triazin-4(3H)-ones which are useful as anti-asthmatic agents.

2-GUANIDINO-4-HETEROARYL-THIAZOLES

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, (2008/06/13)

A series of 2-guanidino-4-heteroarylthiazoles, wherein the heteroaryl substituent is selected from thiazolyl, triazolyl, imidazolyl, and 2-alkyl, 2-amino and 2-carboxamido derivatives thereof, are disclosed. The novel compounds have activity as antisecretory agents and histamine H 2 antagonists and are useful for the treatment of gastric hyperacidity and peptic ulcers. Also disclosed are pharmaceutical compositions containing the novel compounds of this invention and a method of using the compounds in the treatment of gastric hyperacidity and peptic ulcers. Novel intermediates useful in the preparation of the novel antisecretory compounds are also described.

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