Methyl 3-acetoxy-23a-homo-5-cholen-24-oate, also known as Methyl (3β)-3-(acetyloxy)chol-5-ene-24-carboxylate, is an organic compound that serves as an intermediate in the synthesis of various cholesterol derivatives. It is characterized by its unique chemical structure, which includes an acetoxy group and a chol-5-ene backbone.
23357-13-3
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Basic information
- Product Name: methyl 3-acetoxy-23a-homo-5-cholen-24-oate
- Synonyms: methyl 3-acetoxy-23a-homo-5-cholen-24-oate
- CAS NO:23357-13-3
- Molecular Formula:
- Molecular Weight: 444.655
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: methyl 3-acetoxy-23a-homo-5-cholen-24-oate(CAS DataBase Reference)
- NIST Chemistry Reference: methyl 3-acetoxy-23a-homo-5-cholen-24-oate(23357-13-3)
- EPA Substance Registry System: methyl 3-acetoxy-23a-homo-5-cholen-24-oate(23357-13-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 23357-13-3(Hazardous Substances Data)
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23357-13-3 Usage
Uses
1. Used in Pharmaceutical Industry:Methyl 3-acetoxy-23a-homo-5-cholen-24-oate is used as an intermediate for the synthesis of 25-Hydroxy Cholesterol (H918030), an oxygenated derivative of Cholesterol (C432501). This oxysterol has potential applications in the development of drugs targeting cholesterol-related conditions.
2. Used in Antiviral Applications:
Methyl 3-acetoxy-23a-homo-5-cholen-24-oate is used as an antiviral agent for inhibiting human immunodeficiency virus (HIV) replication in vitro. Its ability to interfere with the virus's life cycle makes it a promising candidate for further research and development in the field of HIV treatment.
3. Used in Apoptosis Induction:
Methyl 3-acetoxy-23a-homo-5-cholen-24-oate is used as an apoptosis inducer in human monocytic cell lines. It has been shown to induce apoptosis in CEM cells, which is associated with the negative regulation of c-Myc. This property makes it a potential candidate for the development of therapeutic agents targeting cancer cells and other diseases involving abnormal cell proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 23357-13-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,3,5 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.Calculate Digit Verification of CAS Registry Number 23357-13:
(7*2)+(6*3)+(5*3)+(4*5)+(3*7)+(2*1)+(1*3)=93
93 % 10 = 3
So 23357-13-3 is a valid CAS Registry Number.
23357-13-3Upstream product
23357-13-3Downstream Products
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methyl 3-acetoxy-23a-homo-5-cholen-24-oate
