233744-17-7Relevant academic research and scientific papers
Synthesis based on affinity separation (SAS): Separation of products having barbituric acid tag from untagged compounds by using hydrogen bond interaction
Zhang, San-Qi,Fukase, Koichi,Izumi, Minoru,Fukase, Yoshiyuki,Kusumoto, Shoichi
, p. 590 - 596 (2007/10/03)
A new method is described for affinity purification of synthetic compounds based on molecular recognition between bis(2,6-diaminopyridine)amide of isophthalic acid and a barbituric acid derivative. The desired compounds possessing the barbituric acid deri
A novel oxidatively removable linker and its application to α-selective solid-phase oligosaccharide synthesis on a macroporous polystyrene support
Fukase, Koichi,Nakai, Yoshihiko,Egusa, Kenji,Porco Jr., John A.,Kusumoto, Shoichi
, p. 1074 - 1078 (2007/10/03)
A novel p-acylaminobenzyl-type linker and its application to the solid phase synthesis of oligosaccharides are described. The p-glutarylaminobenzyl ether of a monosaccharide was readily introduced to a polymer support by amide bond formation. The linker moiety was smoothly cleaved by DDQ oxidation. α-Selective glycosylation was accomplished by virtue of the solvent effect of diethyl ether on a solid support of a macroporous polystyrene. High α-selectivity was achieved by the use of benzylated donors possessing the bulky t-butyldiphenylsilyl group at the 6-position.
