233759-71-2Relevant academic research and scientific papers
Synthesis of diether-linked cationic lipids for gene delivery
Ren, Tan,Liu, Dexi
, p. 1247 - 1250 (2007/10/03)
Quaternary ammonium lipids 1b-d, with diether linkages between hydrocarbon chains and butane or hexane backbone, were synthesized for cationic liposome-mediated gene delivery. The synthetic strategy of using C- 4 or C-6 synthon permits the achievement of the variation of the hydrophobic domain as well as changes of space between the quaternary ammonium head and the hydrophobic domain in the diether-linked cationic lipids.
