233767-49-2

Upstream product

• 189766-13-0 (S)S-2-isopropyl-5-p-tolylsulfinyl-1,3,4-trimethoxybenzene 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 60241-78-3 3-(1-methylethyl)-1,2,4-trimethoxybenzene 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 
• 60241-76-1 3-(1-methyl-1-hydroxyethyl)-1,2,4-trimethoxybenzene 

Relevant academic research and scientific papers

ortho-Directed metallation in the regiocontrolled synthesis of enantiopure 2- and/or 3-substituted (S)S (p-tolylsulfinyl)-1,4-benzoquinones

Enantiomerically pure (S)S-(p-tolylsulfinyl)-1,4-benzoquinones with alkyl and methoxy substituents at C-2 and/or C-3 are synthesized by CAN oxidation of adequately substituted (S)S-(p-tolylsulfinyl)-1,4-dimethoxyaromatic precursors 2 or 3. These compounds were obtained by ortho-directed metallation or bromo-metal exchange from the corresponding p-methoxyanisoles in a highly regiocontrolled manner.