234093-70-0Relevant articles and documents
Syntheses of 1,5-benzothiazepines-part XXXI: Syntheses and antimicrobial studies of 10-substituted-7-(monochlorophenyl/dichlorophenyl)-6H-6a,7-dihydro-6- phenyl[1]benzopyrano[3,4-c]-[1,5]benzothiazepines
Pant, Umesh C.,Dandia,Chandra, Hem,Goyal, Shweta,Pant, Seema
, p. 559 - 571 (2005)
Two flavindogenides, 3-(2-chlorobenzylidene)-flavanone and 3-(2,4-dichlorobenzylidene)-flavanone reacted with six 5-substituted-2- aminobenzenethiols, the substituents being fluoro, chloro, bromo, methyl, methoxyl, and ethoxyl, to give respective 12 new compounds, 10-substituted-7-(2- chlorophenyl/2,4-dichlorophenyl)-6H-6a, 7-dihydro-6-phenyl[1]benzopyrano[3,4-c] [1,5]benzothiazepines (5a-l) in 60-70% yields. The products were characterized on the basis of microanalytical data for elements and IR, 1H, and 13C NMR and mass spectral studies. All the synthesized compounds were evaluated for their antimicrobial activity against the bacteria, Escherichia coli and GFC, and the fungi, Aspergillus niger, Aspergillus flavus, and Curvularia lunata. Copyright Taylor & Francis Inc.