2343-29-5

Upstream product

• 1181772-21-3 3'-chlorosulfonyl-4'-fluoroacetophenone 
• 2002-82-6 1-(3-amino-4-fluorophenyl)ethanone 
• 210826-74-7 2-fluoro-5-(2-methyl-[1,3]dioxolan-2-yl)-benzenesulfonamide 

Downstream Products

• 68505-01-1 5-Acetyl-2-ethylamino-benzenesulphonamide 
• 68504-95-0 5-acetyl-2-diethylaminobenzenesulphonamide 
• 68504-92-7 5-acetyl-2-(1-piperidinyl)benzenesulphonamide 
• 68504-99-4 2-amino-5-[1-hydroxy-2-[N-(1-methyl-3-phenylpropyl)-N-(phenylmethyl)amino]ethyl]benzenesulphonamide 
• 68504-86-9 5-(2-Dibenzylamino-acetyl)-2-fluoro-benzenesulfonamide 
• 68504-54-1 2-Fluoro-5-[1-hydroxy-2-[[3-(4-fluorophenyl)-1-methylpropyl]-amino]ethyl]benzenesulphonamide 
• 68504-77-8 2-Fluoro-5-[1-hydroxyl-2-[[3-(3-fluorophenyl)-1-methylpropyl]amino]ethyl]benzenesulphonamide 
• 70958-68-8 2-Amino-5-[1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]benzenesulphonamide 
• 68505-02-2 5-(Bromoacetyl)-2-ethylaminobenzenesulphonamide 
• 68504-85-8 2-bromo-4'-fluoro-3'-sulfamoylacetophenone 
• 68504-97-2 5-Acetyl-2-aminobenzenesulphonamide 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula A, or a pharmaceutically acceptable salt thereof, are featured (Formula A) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formula A can be as defined anywhere herein.

SULPHONAMIDES AND COMPOSITIONS THEREOF FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: wherein the variables shown in Formula AA can be as defined anywhere herein. Compounds AA are modulators of NLRP1 and/or NLRP3

Thiazolidine derivatives

The invention relates to thiazolidine derivatives having in 4-position a hydroxy group and a 3'-sulphamyl-phenyl substituent, in 2-position an imino group and in 1-position an aliphatic or cycloaliphatic substituent. Said thiazolidines have diuretic activity. The invention also relates to a process for the manufacture of said compounds.