234445-61-5

Usage

Uses

Used in Pharmaceutical Industry:
4-Thiazolecarboxylic acid, 2-(1-methylethyl)-(9CI) is used as a chemical reactant for the preparation of new M3 muscarinic antagonists. These antagonists are essential in the development of medications targeting various conditions, such as overactive bladder, chronic obstructive pulmonary disease (COPD), and certain gastrointestinal disorders. The compound's unique structure allows for the creation of novel M3 antagonists with improved efficacy and reduced side effects.
Used in Antifungal Applications:
In the field of antifungal drug development, 4-Thiazolecarboxylic acid, 2-(1-methylethyl)-(9CI) is utilized in the novel synthesis of Cystothiazole C. Cystothiazole C is a potential antifungal agent that shows promise in treating various fungal infections. The compound's incorporation into the synthesis process contributes to the development of new antifungal drugs with enhanced potency and selectivity, offering better treatment options for patients suffering from fungal infections.

InChI:InChI=1/C7H9NO2S/c1-4(2)6-8-5(3-11-6)7(9)10/h3-4H,1-2H3,(H,9,10)

Upstream product

• 336193-96-5 methyl 2-isopropylthiazole-4-carboxylate 

Downstream Products

• 1180495-68-4 N-(6-acetyl-2-chloro-3-methoxyphenyl)-2-isopropylthiazole-4-carboxamide 
• 1261242-67-4 C₂₂H₂₈ClN₃O₂S 
• 1261242-70-9 C₂₂H₂₈ClN₃O₂S 
• 1261242-69-6 C₂₂H₂₈ClN₃O₂S 
• 1261242-68-5 C₂₂H₂₉N₃O₂S 
• 1310551-52-0 2-Isopropyl-thiazole-4-carboxylic acid [6-acetyl-2-chloro-3-(2,2-dimethoxy-ethoxy)-phenyl]-amide 
• 1414360-76-1 2-[2-fluoro-5-[[4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]methyl]phenyl]acetaldehyde 
• 1414360-85-2 [9-[[3-[2-[benzyl-[(2R)-2-(4-tert-butoxy-2-isopropoxy-1,3-benzothiazol-7-yl)-2-hydroxyethyl]amino]ethyl]-4-fluorophenyl]methyl]-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]-(2-isopropylthiazol-4-yl)methanone 
• 1414360-83-0 [9-[[3-[2-(benzylamino)ethyl]-4-fluorophenyl]methyl]-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]-(2-isopropylthiazol-4-yl)methanone 
• 1414360-78-3 [9-[(3-bromo-4-fluorophenyl)methyl]-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl]-(2-isopropylthiazol-4-yl)methanone 
• 1414360-79-4 3-[2-fluoro-5-[[4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]methyl]phenyl]prop-2-enamide 
• 1414360-80-7 3-[2-fluoro-5-[[4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]methyl]phenyl]propanamide 
• 1414397-22-0 C₂₄H₃₃FN₄O₂S 
• 1414360-84-1 2-[benzyl-[2-[2-fluoro-5-[[4-(2-isopropylthiazole-4-carbonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]methyl]phenyl]ethyl]amino]-1-(4-tert-butoxy-2-isopropoxy-1,3-benzothiazol-7-yl)ethanone 

Relevant academic research and scientific papers

Concise synthesis of 2,4-disubstituted thiazoles from β-azido disulfides and carboxylic acids or anhydrides: Asymmetric synthesis of cystothiazole C

A novel and efficient method for the one-pot synthesis of 2,4-disubstituted thiazoles from carboxylic acids or anhydrides is presented. Based on this new method, the total synthesis of the bis-2,4-disubstituted bis(thiazoles) natural product cystothiazole C is also presented. This journal is