234445-91-1Relevant academic research and scientific papers
Synthesis and reactions of new alkynyl substituted nitroxide radicals
Sar, Cecilia P.,Jekoe, Jozsef,Fajer, Peter,Hideg, Kalman
, p. 1039 - 1045 (1999)
N-Oxylpyrrolidine radicals substituted with electron-withdrawing group activated olefinic or acetylenic group 2a-2h, 4, 5, 6 were synthesised from the pyrroline nitrone 1 or from aromatic aldehydes and the alkynylmagnesium bromide of 3. The mercury-catalyzed hydration of alkynyl groups of 2b,c led to the formation of ketones which could be brominated to yield new SH- specific spin labels. The alkynylmagnesium reagent 3 also proved to be versatile in the synthesis of bi- and triradicals 7, 9, 10 and spin labelled steroid derivatives 2e, 12d, 20-22.
