234446-07-2

Upstream product

• 917-64-6 methyl magnesium iodide 
• 61856-60-8 5,5-dimethyl-2-phenacyl-1-pyrroline-1-oxide 
• 170810-90-9 C₁₅H₁₈NO 
• 4567-18-4 2,5,5-trimethylpyrroline N-oxide 
• 176236-99-0 5,8,8-trimethyl-3-phenyl-2-oxa-1-azabicyclo<3,3>oct-3-ene 
• 536-74-3 phenylacetylene 
• 234446-06-1 2-(2-Hydroxy-2-phenylethyl)-2,5,5-trimethylpyrrolidine-1-yloxyl radical 

Downstream Products

• 234446-09-4 2-(1-Bromo-2-oxo-2-phenylethyl)-2,5,5-trimethylpyrrolidin-1-yloxyl radical 

Relevant academic research and scientific papers

Synthesis and reactions of new alkynyl substituted nitroxide radicals

N-Oxylpyrrolidine radicals substituted with electron-withdrawing group activated olefinic or acetylenic group 2a-2h, 4, 5, 6 were synthesised from the pyrroline nitrone 1 or from aromatic aldehydes and the alkynylmagnesium bromide of 3. The mercury-catalyzed hydration of alkynyl groups of 2b,c led to the formation of ketones which could be brominated to yield new SH- specific spin labels. The alkynylmagnesium reagent 3 also proved to be versatile in the synthesis of bi- and triradicals 7, 9, 10 and spin labelled steroid derivatives 2e, 12d, 20-22.

Interaction of 5,5-dimethyl-2-phenacylpyrroline-1-oxide - An exocyclic β-oxonitrone - With nucleophilic reagents

A study has been made of the interaction of 2,5,5-trimethylpyrroline-1-oxide with ethyl formate, ethyl thiobenzoate, and methyl nitrate. It has been shown that the reaction of 5,5-dimethyl-2-phenacylpyrroline-1-oxide with methylmagnesium iodide or phenyll