23446-11-9

Basic information

• Product Name: BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8)
• Synonyms: N-ALPHA-T-BOC-MET-GLY-TRP-MET-ASP-PHE NH2;BOC-MET-GLY-TRP-MET-ASP-PHE-NH2;BOC-CCK 28-33;BOC-CHOLECYSTOKININ 28-33;BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8);Boc-CCK-6;Boc-L-Met-Gly-L-Trp-L-Met-L-Asp-L-Phe-NH2
• CAS NO: 23446-11-9
• Molecular Formula: C₄₁H₅₆N₈O₁₀S₂
• Molecular Weight: 885.06
• EINECS: 1533716-785-6
• Mol File: 23446-11-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8)(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8)(23446-11-9)
• EPA Substance Registry System: BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8)(23446-11-9)

Safety Data

• Hazardous Substances Data: 23446-11-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8) is used as a research tool for studying the pharmacological effects of CCK. It helps in understanding the role of CCK in appetite regulation, digestion, and pain perception, which are essential for developing potential therapeutic interventions for conditions related to CCK dysregulation.
Used in Obesity Treatment:
BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8) is used as a potential therapeutic agent for obesity treatment. Its ability to modulate appetite regulation makes it a promising candidate for developing drugs that can help control food intake and promote weight loss.
Used in Gastrointestinal Disorders:
BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8) is used as a potential therapeutic agent for gastrointestinal disorders. Its role in digestion regulation can help in managing conditions such as irritable bowel syndrome, inflammatory bowel disease, and other gastrointestinal motility disorders.
Used in Pain Management:
BOC-CHOLECYSTOKININ OCTAPEPTIDE (3-8) is used as a potential therapeutic agent for pain management. Its ability to modulate pain perception can be utilized in developing drugs for chronic pain conditions, such as neuropathic pain, inflammatory pain, and postoperative pain.

Upstream product

• 5934-92-9 MDF_NH2 
• 115967-21-0 tert-butyloxycarbonylmethionyl-glycyl-tryptophan 
• 5549-48-4 H-Trp-Met-Asp-Phe-NH₂*TFA 
• 103088-16-0 Boc-Met-Gly-OCp 
• 2488-15-5 N-tert-butoxycarbonyl-L-methionine 
• 7536-58-5 BOC-L-aspartic acid 4-benzyl ester 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 47355-10-2 Nα-tert-butoxycarbonyl-1-formyl-L-tryptophan 
• 23446-03-9 2-((2S)-2-((tert-butoxycarbonyl)amino)-4-(methylthio)butanamido)acetic acid 
• 16948-13-3 Boc-Met-OTcp 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 
• 113709-64-1 tert-butyloxycarbonylmethionyl-glycyl-tryptophan methyl ester 

Downstream Products

• 92409-86-4 methionyl-glycyl-tryptophyl-methionyl-aspartyl-phenylalanine amide trifluoroacetate 
• 21163-42-8 H-Met-Gly-Trp-Met-Asp-Phe-NH₂ (CCK-6) 

Relevant articles and documents

SYNTHESIS AND BIOLOGICAL PROPERTIES OF CHOLECYSTOKININ HEPTAPEPTIDE ANALOGUES CONTAINING D- AND L-FORMS OF TERT-LEUCINE OR NEOPENTYLGLYCINE IN POSITION 5

Using solution or solid-phase synthesis we prepared the cholecystokinin fragment Boc-CCK-7 (Boc-Tyr-(SO3-*Na+)-Met-Gly-Trp-Met-Asp-PheNH2) and its four analogues in which the methionine moiety (Met) in the carboxy-terminal part is re

SYNTHESIS OF THE CARBOXY-TERMINAL OCTAPEPTIDE OF CHOLECYSTOKININ (CCK-8) BASED ON INCORPORATION OF O4-SULFOTYROSINE BY ENZYMATICALLY CATALYZED FORMATION OF PEPTIDE BONDS

Papain-catalyzed condensation of sodium salt of tert-butyloxycarbonyl-β-tert-butyloxyaspartyl-O4-sulfotyrosine (fragment 1-2) with methionyl-glycyl-tryptophyl-methionyl-aspartyl-phenylalanine amide (fragment 3-8) has been elaborated.Deprotectio