9-oxo-11R,15S-dihydroxy-1a,1b-dihomo-13E-prostaenoic acid is a bioactive lipid molecule that belongs to the class of dihydroxyeicosatrienoic acids (DHETs). It is derived from the metabolism of arachidonic acid and acts as a potent agonist of peroxisome proliferator-activated receptor gamma (PPARγ). This molecule plays a crucial role in the regulation of glucose and lipid metabolism and has been found to exhibit anti-inflammatory properties. Its potential therapeutic implications include the treatment of metabolic syndrome, diabetes, and cardiovascular diseases. Further research is needed to fully understand its physiological and pharmacological functions.
23452-98-4
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Basic information
- Product Name: 1A,1B-DIHOMO PROSTAGLANDIN E1
- Synonyms: 9-OXO-11ALPHA,15S-DIHYDROXY-1A,1B-DIHOMO-PROST-13E-EN-1-OIC ACID;1A,1B-DIHOMO PROSTAGLANDIN E1;YMDDELUTDBQEMT-QZCLESEGSA-N;1a,1b-dihomo PGE1;9-oxo-11α,15S-dihydroxy-1a,1b-dihomo-prost-13E-en-1-oic acid
- CAS NO:23452-98-4
- Molecular Formula: C22H38O5
- Molecular Weight: 382.53
- EINECS: N/A
- Product Categories: N/A
- Mol File: 23452-98-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1A,1B-DIHOMO PROSTAGLANDIN E1(CAS DataBase Reference)
- NIST Chemistry Reference: 1A,1B-DIHOMO PROSTAGLANDIN E1(23452-98-4)
- EPA Substance Registry System: 1A,1B-DIHOMO PROSTAGLANDIN E1(23452-98-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 23452-98-4(Hazardous Substances Data)
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23452-98-4 Usage
Uses
Used in Pharmaceutical Industry:9-oxo-11R,15S-dihydroxy-1a,1b-dihomo-13E-prostaenoic acid is used as a therapeutic agent for the treatment of metabolic syndrome, diabetes, and cardiovascular diseases due to its ability to regulate glucose and lipid metabolism and its anti-inflammatory properties.
Used in Drug Development:
9-oxo-11R,15S-dihydroxy-1a,1b-dihomo-13E-prostaenoic acid is used as a lead compound in drug development for the discovery of new medications targeting metabolic disorders and inflammatory conditions, given its agonistic effect on PPARγ and its potential to modulate various signaling pathways involved in these diseases.
Used in Research:
9-oxo-11R,15S-dihydroxy-1a,1b-dihomo-13E-prostaenoic acid is used as a research tool to study the molecular mechanisms underlying the regulation of glucose and lipid metabolism, as well as the role of PPARγ in various physiological and pathological processes. This helps in understanding the potential therapeutic applications of this molecule and its analogs in the treatment of related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 23452-98-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,4,5 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.Calculate Digit Verification of CAS Registry Number 23452-98:
(7*2)+(6*3)+(5*4)+(4*5)+(3*2)+(2*9)+(1*8)=104
104 % 10 = 4
So 23452-98-4 is a valid CAS Registry Number.
23452-98-4Upstream product
23452-98-4Downstream Products
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1A,1B-DIHOMO PROSTAGLANDIN E1
