23459-36-1

Usage

Uses

Used in Psychoactive Substance Research:
Cyclopentyl(phenyl)methanamine is used as a research compound for studying its psychoactive effects and potential applications in the field of psychopharmacology. Its stimulant properties and similarities to amphetamine make it a subject of interest for understanding the mechanisms of action and potential therapeutic uses.
Used in Pharmaceutical Development:
Cyclopentyl(phenyl)methanamine is used as a starting material or intermediate in the development of new pharmaceuticals targeting the central nervous system. Its structural and functional properties may contribute to the creation of novel drugs with improved efficacy and safety profiles.
Used in Forensic Toxicology:
Cyclopentyl(phenyl)methanamine is used as a reference compound in forensic toxicology for the identification and analysis of substances in biological samples. Its controlled status and potential for abuse make it a relevant target for detection in cases of drug abuse or intoxication.
Used in Regulatory and Law Enforcement:
Cyclopentyl(phenyl)methanamine is used as a reference substance in regulatory and law enforcement agencies to monitor and control its distribution, sale, and use. Its classification as a controlled substance requires strict regulation to prevent abuse and ensure public safety.

Upstream product

• 110480-94-9 cyclopentylphenylmethanol 
• 151-50-8 potassium cyanide 
• 83568-09-6 cyclopentyl phenyl ketoxime 
• 5422-88-8 phenyl cyclopentyl ketone 
• 77287-34-4 formamide 
• 93141-99-2 syn-Cyclopentyl-phenyl-keton-(O-2-dimethylamino-aethyl-oxim) 
• 790201-65-9 N-(cyclopentyl(phenyl)methyl)formamide 
• 4524-93-0 Cyclopentanecarboxylic acid chloride 
• 3400-45-1 cyclopentanecarboxylic acid 
• 100-47-0 benzonitrile 
• 33240-34-5 cyclopentylmagnesium bromide 
• 100-46-9 benzylamine 

Downstream Products

• 439287-36-2 2-[(cyclopentyl-phenyl-methyl)-carbamoyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 144983-34-6 1-(2-phenylbenzoxazol-7-yl)-3-[(1-phenylcyclopentyl)methyl]urea 
• 326894-43-3 (-)-(S)-N-(cyclopentylphenylmethyl)acetamide 

Relevant academic research and scientific papers

Transition-Metal-Free C(sp3)a'H Coupling of Cycloalkanes Enabled by Single-Electron Transfer and Hydrogen Atom Transfer

Here we report a unique transition-metal-free C(sp3)-H/C(sp3)-H coupling of cycloalkanes at room temperature. Unactivated cycloalkanes and 2-azaallyls underwent the combination process of single-electron transfer (SET) and hydrogen atom transfer (HAT) to deliver a wide variety of cycloalkane-functionalized products. This expedient approach enables C(sp3)-H/C(sp3)-H coupling of cycloalkanes under mild conditions without transition metals, initiators, and oxidants.

Method for synthesizing S-shaped amino compound

The invention discloses a method for synthesizing S-shaped amino compound, namely, S-alpha-cyclopentyl(phenyl)methylamine. The method includes the steps of using cyclopentyl phenyl ketone as a raw material, allowing cyclopentyl phenyl ketone to react with

Method for synthesizing medical intermediates

The invention discloses a method for synthesizing medical intermediates R-alpha-cyclopentyl (phenyl) methylamine. The particular method includes generating racemization alpha-cyclopentyl (phenyl) methylamine from phenyl cyclopentanone by means of reductiv

BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS

The present invention relates to Bicyclic Heterocycle Derivatives of formula (I), compositions comprising a Bicyclic Heterocycle Derivative, and methods of using the Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of GPR1 19 in a patient.

Synthesis and structure-activity relationships of potential anticonvulsants based on 2-piperidinecarboxylic acid and related pharmacophores

Using N-(2,6-dimethyl)phenyl-2-piperidinecarboxamide (1) and N-(α-methylbenzyl)-2-piperidinecarboxamide (2) as structural leads, a variety of analogues were synthesised and evaluated for anticonvulsant activity in the MES test in mice. In the N-benzyl series, introduction of 3-Cl, 4-Cl, 3,4-Cl2, or 3-CF3 groups on the aromatic ring led to an increase in MES activity. Replacement of the α-methyl group by either i-Pr or benzyl groups enhanced MES activity with no increase in neurotoxicity. Substitution on the piperidine ring nitrogen led to a decrease in MES activity and neurotoxicity, while reduction of the amide carbonyl led to a complete loss of activity. Movement of the carboxamide group to either the 3- or 4-positions of the piperidine ring decreased MES activity and neurotoxicity. Incorporation of the piperidine ring into a tetrahydroisoquinoline or diazahydrinone nucleus led to increased neurotoxicity. In the N-(2,6-dimethyl)phenyl series, opening of the piperidine ring between the 1- and 6-positions gave the active norleucine derivative 75 (ED50 = 5.8 mg kg-1, TD50 = 36.4 mg kg-1, PI = 6.3). Replacement of the piperidine ring of 1 by cycloalkane (cyclohexane, cyclopentane, and cyclobutane) resulted in compounds with decreased MES activity and neurotoxicity, whereas replacement of the piperidine ring by a 4-pyridyl group led to a retention of MES activity with a comparable PI. Simplification of the 2-piperidinecarboxamide nucleus of 1 into a glycinecarboxamide nucleus led to about a six-fold decrease in MES activity. The 2,6-dimethylanilides were the most potent compounds in the MES test in each group of compounds evaluated, and compounds 50 and 75 should be useful leads in the development of agents for the treatment of tonic-clonic and partial seizures in man.

Hypoglycemic α cycloalkylphenylmethyl, furanalkyl, and thiophenealkyl lactamimides

A series of α cycloalkylphenylmethyl lactamimides and a series of furan and thiophenealkyl lactamimides were prepared for biological evaluation as an extension of earlier findings of hypoglycemic activity in lactamimides. Several compounds produced pronouced hypoglycemia after oral administration to fasted, glucose primed rats.