234755-01-2

Upstream product

• 144492-44-4 (4R)-benzyliminomethyl-2,2-dimethyloxazolidine-3-carboxylic acid 1,1-dimethylethyl ester 
• 1066-54-2 trimethylsilylacetylene 
• 102308-32-7 (4S)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 100-46-9 benzylamine 

Downstream Products

• 234755-06-7 acetic acid 3(S)-{benzyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2(R)-{[(tert-butoxy)carbonyl]amino}-5-(trimethylsilyl)pent-4-yn-1-yl ester 
• 234755-11-4 tert-butyl (1S,4R)-2-[N-(9H-fluoren-9-ylmethoxycarbonyl)-benzylamino]-(1-hydroxymethyl-4-trimethylsilylbut-3-ynyl)carbamate 
• 234755-09-0 tert-butyl (3aR,4R)-3-benzyl-4-acetoxymethyl-2-oxo-1-p-toluenesulfonyl-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-d]imidazole-5-carboxylate 
• 234755-04-5 tert-butyl (3aR,4R)-3-benzyl-4-isopropenyloxymethyl-2-oxo-1-p-toluenesulfonyl-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-d]imidazole-5-carboxylate 
• 234755-10-3 tert-butyl (1S,4R)-[1-benzyl-(9H-fluoren-9-ylmethoxycarbonylamino)]-2,2-dimethyloxazolidine-3-carboxylate 

Relevant academic research and scientific papers

Alkylidenecarbene insertion into a nitrogen lone pair: An unexpected synthesis of dihydropyrroles from alkynyliodonium salts

A novel intramolecular reaction between an alkylidenecarbene and the lone pair of electrons on a carbamate's nitrogen is described. The reaction occurs preferentially over an available 1,5 C-H insertion and gives substituted dihydropyrroles upon workup.