234768-79-7Relevant academic research and scientific papers
N-formyl hydroxylamine derivatives as antibacterial agents
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, (2008/06/13)
Compounds of formula (I) are in the preparation of antibacterial agents, wherein: R1represents hydrogen, C1-C6alkyl or C1-C6alkyl substituted by one or more halogen atoms; R2represents a group R10(X)n—(ALK)— wherein R10represents hydrogen, a C1-C6alkyl, C2-C6alkenyl, C1-C6alkynyl, cycloalkyl, aryl, or heterocyclyl group, any of which may be unsubstituted or substituted by (C1-C6)alkyl, (C1-C6)alkoyy, hydroxy, mercapto, (C1-C6)alkylthio, amino, halo, trifluoromethyl, cyano, nitro, —COOH, —CONH2, —COORA, —NHCORA, —CONHRA, —NHRA, —NRARB, or —CONRARBwherein RAand RBare independently a (C1-C6)alkyl group, and ALK represents a straight or branched divalent C1-C6alkylene, C2-C6alkenylene, or C2-C6alkynylene radical, which may be interrupted by one or more non-adjacent —NH—, —O— or —S— linkages, X represents —NH—, —O— or —S—, and n is 0 or 1, R represents hydrogen or C1-C6alkyl, R3represents the characterising group or a natural or non-natural α amino acid in which any functional groups may be protected; and R4represents an ester or thioester group.
Cytostatic agents
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, (2008/06/13)
Compounds of formula (I) wherein R4 is an ester or thioester group and R, R1, R2 and R3 are as defined in the specification, inhibit proliferation of tumor cells.
