234774-56-2Relevant academic research and scientific papers
Lipase-catalyzed regioselective domino reaction for the synthesis of chromenone derivatives
Yang, Qi,Zhou, Long-Hua,Wu, Wan-Xia,Zhang, Wei,Wang, Na,Yu, Xiao-Qi
, p. 78927 - 78932 (2015)
An efficient synthesis of 2H-chromenones and 2-hydroxyl-2H-chromenones derivatives has been developed from 1,3-dicarbonyls and α,β-unsaturated aldehydes by a controllable regioselective domino cyclization reaction under catalysis of different lipases. 2H-Chromenones derivatives were synthesized by bovine pancreatic lipase (BPL) in acetonitrile, while lipase from Pseudomonas fluorescens (PFL) can catalyze the synthesis of the 2-hydroxyl-2H-chromenones derivatives in dichloromethane with moderate to high yields.
Formal cycloaddition reactions of vinylogous amides with α,β-Unsaturated iminiums. A strategy for constructing piperidinyl heterocycles
Hsung, Richard P.,Wei, Lin-Li,Sklenicka, Heather M.,Douglas, Christopher J.,McLaughlin, Michael J.,Mulder, Jason A.,Yao, Letitia J.
, p. 509 - 512 (1999)
(Formula presented) A formal [3 + 3] cycloaddition strategy for constructing piperidinyl heterocycles from vinylogous amides and α,β-unsaturated iminiums is described here. These reactions proceed well, leading to various heterocycles that could serve as
A Lewis acid-catalyzed formal [3 + 3] cycloaddition of α,β- unsaturated aldehydes with 4-hydroxy-2-pyrone, diketones, and vinylogous esters
Kurdyumov, Aleksey V.,Lin, Nan,Hsung, Richard P.,Gullickson, Glen C.,Cole, Kevin P.,Sydorenko, Nadiya,Swidorski, Jacob J.
, p. 191 - 193 (2007/10/03)
A Lewis acid-catalyzed formal cycloaddition of α,β-unsaturated aldehydes with 6-methyl-4-hydroxy-2-pyrone, 1,3-diketones, and vinylogous silyl esters is described here.
A formal [3 + 3] cycloaddition reaction. Improved reactivity using α,β-unsaturated iminium salts and evidence for reversibility of 6π-electron electrocyclic ring closure of 1-oxatrienes
Shen, Hong C.,Wang, Jiashi,Cole, Kevin P.,McLaughlin, Michael J.,Morgan, Christopher D.,Douglas, Christopher J.,Hsung, Richard P.,Coverdale, Heather A.,Gerasyuto, Aleksey I.,Hahn, Juliet M.,Liu, Jia,Sklenicka, Heather M.,Wei, Lin-Li,Zehnder, Luke R.,Zificsak, Craig A.
, p. 1729 - 1735 (2007/10/03)
A detailed account regarding a formal [3 + 3] cycloaddition method using 4-hydroxy-2-pyrones and 1,3-diketones is described here. This formal cycloaddition reaction or annulation reaction is synthetically useful for constructing 2H-pyranyl heterocycles. T
