2350-32-5

Basic information

• Product Name: Butoxycainhydrochlorid
• Synonyms: ButoxycainHCl;Butoxycainhydrochlorid;BUTOXYCAINE HYDROCHLORIDE;Butoxycaine;2-diethylaminoethyl 4-butoxybenzoate hydrochloride;4-butoxybenzoic acid 2-diethylaminoethyl ester hydrochloride
• CAS NO: 2350-32-5
• Molecular Formula: C17H28ClNO3
• Molecular Weight: 329.86212
• Mol File: 2350-32-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 146°
• Boiling Point: 435.25°C (rough estimate)
• Flash Point: 192.7°C
• Appearance: /
• Density: 1.0112 (rough estimate)
• Vapor Pressure: 1.89E-06mmHg at 25°C
• Refractive Index: 1.5420 (estimate)
• Water Solubility: 38.14mg/L(temperature not stated)
• CAS DataBase Reference: Butoxycainhydrochlorid(CAS DataBase Reference)
• NIST Chemistry Reference: Butoxycainhydrochlorid(2350-32-5)
• EPA Substance Registry System: Butoxycainhydrochlorid(2350-32-5)

Safety Data

• Hazardous Substances Data: 2350-32-5(Hazardous Substances Data)

Usage

Uses

Butoxycaine is one of the many in combination drugs used in anesthetics as cardiovascular agent, hypnotics, anesthetics and analgesics.

InChI:InChI=1/C17H27NO3/c1-4-7-13-20-16-10-8-15(9-11-16)17(19)21-14-12-18(5-2)6-3/h8-11H,4-7,12-14H2,1-3H3

Upstream product

• 100-37-8 2-(Diethylamino)ethanol 
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Relevant articles and documents

Micellisation as the origin of the 'cut off'-effect in homologous series of surface anaesthetics

On the example of the surface anaesthetic homologous series of 4-alkoxybenzoic-diethylaminoethylester-HCl (parethoxycaine) the so-called 'cut off'-effect was studied. The 'cut off'-effect is the phenomenon, that a weaker efficiency or an unefficiency is observed on the higher homologues of therapeutic substances. It is demonstrated that the 'cut off'-effect is referred to the micellisation and aggregation of the higher homologues of the local anaesthetics in aqueous solution. This has the consequence, that the higher homologues cannot diffuse on the pain receptors and so the efficiency is reduced. By the addition of urea the aggregation will be reduced and the chain length-efficiency curve will take a different course.