23515-80-2

Usage

Chemical family

Indole

Functional groups

Nitro group, phenyl group

Unique chemical properties

The presence of the nitro and phenyl groups attached to the indole ring

Potential pharmaceutical applications

The compound may have potential biological activities that make it a valuable target for further research and development in the field of medicinal chemistry.

Uses

Commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and organic compounds due to its versatile reactivity and structure.

Upstream product

• 67571-24-8 α-[1-(4-nitrophenyl)hydrazin-2-ylidene]benzenepropanenitrile 
• 6731-58-4 ethyl 2-cyano-3-phenylpropanoate 
• 100-01-6 4-nitro-aniline 

Relevant academic research and scientific papers

Indole compounds and process for their preparation

Indole compounds having utility as blood platelet aggregation inhibitors and as intermediates in the production of 1,4-benzodiazepines are disclosed.

Preparation of indole derivatives

An improved process for preparing indole derivatives of the formula, STR1 wherein R1 and R2 each are hydrogen, halogen, C1 -C3 alkyl, C1 -C3 alkoxy, nitro, cyano or trifluoromethyl, or when taken together, form methylenedioxy; R3 is hydrogen, halogen, C1 -C3 alkyl, C1 -C3 alkoxy, nitro, cyano or dimethylamino; and R4 is hydrogen or halogen, which comprises cyclizing a compound of the formula, STR2 wherein R1, R2, R3 and R4 are as defined above, with an acidic condensing agent. The indole derivatives of the formula (I) mentioned above are useful as a key intermediate for the preparation of benzodiazepines, which are useful as tranquilizers, muscle relaxants and the like.