2353-82-4Relevant academic research and scientific papers
Efficient microscale preparation of isotopically enriched 1-[ 79Br]bromo-2-fluoroethylene, [79Br]BrHC=CHF
Baldan, Alessandro,Tassan, Augusto
, p. 1447 - 1453 (2007/10/03)
An efficient preparation of 1-[79Br]bromo-2-fliioroethylene, [79Br]BrHC= CHF, was carried out by a three-step procedure: (a) natural 1-bromo-2-fluoroethylene, BrHC=CHF, was iodinated to 1-fluoro-2-iodoethylene, FHC=CHI; (b) 1-fluoro-2-iodoethylene was 79Br2-brominated to 1,2-di[79Br]bromo-1-fluoro- 2-iodoethane, [79Br]BrFCHCH[79Br]BrI; and (c) 1,2-di[ 79Br]bromo-1-fluoro-2-iodoethane was dehalogenated to 1-[ 79Br]bromo-2-fluoroethylene, [79Br]BrHC=CHF. The yield of isolated product, on a 2-mmol scale, was 62% with respect to 79Br2. Copyright Taylor & Francis, Inc.
