23535-28-6

Basic information

• Product Name: 1-Piperidineacetic acid, a-phenyl-, methyl ester
• CAS NO: 23535-28-6
• Molecular Formula: C14H19NO2
• Molecular Weight: 233.31
• Mol File: 23535-28-6.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-Piperidineacetic acid, a-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidineacetic acid, a-phenyl-, methyl ester(23535-28-6)
• EPA Substance Registry System: 1-Piperidineacetic acid, a-phenyl-, methyl ester(23535-28-6)

Safety Data

• Hazardous Substances Data: 23535-28-6(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 278605-08-6 5-chloro-n-pentylmagnesium bromide 
• 101-41-7 benzeneacetic acid methyl ester 
• 22979-35-7 Methyl phenyldiazoacetate 
• 13887-54-2 methyl 2-methoxy-2-(piperidin-1-yl)acetate 
• 98-80-6 phenylboronic acid 
• 2156-71-0 N-chloropiperidine 
• 213339-69-6 1-(triisopropylsilyloxy)-1-methoxy-2-phenylethylene 
• 108-86-1 bromobenzene 
• 4358-87-6 (RS)-methyl mandelate 
• 107416-49-9 phenyl(piperidin-1-yl)acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 29810-10-4 methyl α-(N,N-dimethylamino)phenylacetate 
• 100609-39-0 methyl 2-phenyl-2-(pyrrolidin-1-yl)acetate 
• 1380490-89-0 methyl 2-(n-(4-bromobutyl)cyanamido)-2-phenylacetate 
• 1380490-87-8 methyl 2-(n-methylcyanamido)-2-phenylacetate 
• 1380490-88-9 methyl 2-((4-chlorobutyl)(ethoxycarbonyl)amino)-2-phenylacetate 
• 7476-66-6 methyl 2-chloro-2-phenylethanoate 
• 1380490-86-7 methyl 2-((ethoxycarbonyl)methylamino)-2-phenylacetate 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 1276118-69-4 C₁₅H₂₀N₂O 
• 1276118-80-9 C₁₇H₂₆N₂O₂ 
• 1276118-72-9 C₁₇H₂₄N₂O 
• 1276118-71-8 C₁₆H₂₂N₂O 
• 1276118-70-7 C₁₆H₂₂N₂O 
• 1276118-79-6 C₁₇H₂₂N₂O₂ 

Relevant articles and documents

Electrochemical Oxidative Coupling between Benzylic C(sp3)-H and N-H of Secondary Amines: Rapid Synthesis of α-Amino α-Aryl Esters

An intermolecular electrochemical coupling between the benzylic C(sp3)-H bond and various secondary amines is reported. The electronic behavior of two electronically rich units viz the α-position of α-aryl acetates and amines was engineered electrochemically, thus facilitating their reactivity for the direct access of α-amino esters. A series of acyclic/cyclic secondary amines and α-aryl acetates were tested to furnish the corresponding α-amino esters with high yields (up to 92%) under mild conditions.

Enantioselective Palladium-Catalyzed Carbene Insertion into the N?H Bonds of Aromatic Heterocycles

C3-substituted indoles and carbazoles react with α-aryl-α-diazoesters under palladium catalysis to form α-(N-indolyl)-α-arylesters and α-(N-carbazolyl)-α-arylesters. The products result from insertion of a palladium-carbene ligand into the N?H bond of the aromatic N-heterocycles. Enantioselection was achieved using a chiral bis(oxazoline) ligand, in many cases with high enantioselectivity (up to 99 % ee). The method was applied to synthesize the core of a bioactive carbazole derivative in a concise manner.

Synthesis and characterization of bisoxazolines- and pybox-copper(II) complexes and their application in the coupling of α-carbonyls with functionalized amines

Binuclear complexes [{(DMOX)CuCl}2(μ-Cl)2] (1), mononuclear complexes [(DMOX)CuBr2] (2) (DMOX = 4,5-dihydro-2-(4,5- dihydro-4,4-dimethyloxazol-2-yl)-4,4-dimethyloxazole) and the pybox Cu(ii) complex [(Dm-Pybox)CuBr2/