235426-30-9 Usage
Uses
Used in Pharmaceutical Research:
2-Bromo-1,4-dimethyl-1H-imidazole is used as an intermediate in pharmaceutical research for the synthesis of various drug candidates. Its unique structure allows for the development of new compounds with potential therapeutic applications.
Used in Organic Chemistry:
2-Bromo-1,4-dimethyl-1H-imidazole is used as a building block in the synthesis of more complex organic compounds. Its reactivity and structural features make it a valuable component in the creation of novel molecules with diverse properties and potential applications in various industries.
Used in Scientific Research:
2-Bromo-1,4-dimethyl-1H-imidazole is employed as a research tool in various scientific studies, particularly in the field of chemistry. Its properties and reactivity are investigated to gain insights into the behavior of similar compounds and to develop new synthetic strategies and methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 235426-30-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,5,4,2 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 235426-30:
(8*2)+(7*3)+(6*5)+(5*4)+(4*2)+(3*6)+(2*3)+(1*0)=119
119 % 10 = 9
So 235426-30-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H7BrN2/c1-4-3-8(2)5(6)7-4/h3H,1-2H3
235426-30-9Relevant academic research and scientific papers
Reaction of imidazoles with cyanogen bromide: Cyanation at N 1 or bromination at C 2?
McCallum, Peter B.W.,Weavers, Rex T.,Grimmett, M. Ross,Blackman, Allan G.
, p. 159 - 165 (2007/10/03)
The reaction in acetonitrile solution of a number of imidazoles (1H-, 1-methyl-, 2-methyl-, 4-methyl-, 1,2-, 1,4- and 1,5-dimethyl-, 1-ethyl-, 1-benzyl- and 1-butyl-imidazole) and imidazole complexes ([Co(NH3)5(imH)](ClO4)3, [Co(NH3)5(im)] (ClO4)2 and [Co(NH3)5(1-Meim)] (ClO4)3) with BrCN has been studied. Those imidazoles bearing an N-alkyl substituent and having a hydrogen at C2 react to give the 2-bromo products, while the N-H imidazoles react to give W-cyano derivatives. The product(s) from the reaction of 1,2-dimethylimidazole with BrCN could not be characterized. Of the complexes, only [Co(NH3)5(im)] (ClO4)2 reacts, giving the 2-bromo product. Our observations suggest a lone pair on a ring nitrogen atom is necessary for an imidazole to react with BrCN, and a possible mechanism is suggested. The X-ray structure of 2-methylimidazole-1-carbonitrile is reported. Crystal data (-143°C) for C5H5N3: monoclinic, P21/c, a 10.201(5), b 7.110(3), c 7.227(3) A, β 100.47(2)°, V 515.4(4) A3, Z 4, dcalcd 1-380 g cm-3. Refinement of the structure converged with R1 0.0444 for 1183 reflections with Fo > 4F(Fo) and ωR2 0.1259 for all 1278 data.
