23544-42-5

Usage

Uses

Used in Pharmaceutical Industry:
(3aS,6R,7aS)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol is used as a potential candidate for the development of new drugs, specifically for targeting neurological disorders. Its unique structure and potential biological activities suggest that it may offer novel therapeutic approaches in this field.
Used in Medicinal Chemistry:
In the realm of medicinal chemistry, (3aS,6R,7aS)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol is utilized for its potential to contribute to the discovery and design of innovative pharmaceutical agents. (3aS,6R,7aS)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol's specific structural features may facilitate the exploration of new chemical spaces and the optimization of drug candidates.
Further research is necessary to fully understand and harness the properties and applications of (3aS,6R,7aS)-3a-(3,4-dimethoxyphenyl)-1-methyloctahydro-1H-indol-6-ol, ensuring its potential is realized in the advancement of medical treatments and chemical knowledge.

Upstream product

• 156487-74-0 (1S,4R,5S,6S)-4,5-Bis(methoxymethoxy)-1-(3,4-dimethoxyphenyl)-7,9-dioxabicyclo<4.3.0>nonane-8-thione 
• 156487-73-9 1L-<1(OH),2,3/4>-3,4-Bis-O-(methoxymethyl)-1-(3,4-dimethoxyphenyl)cyclohex-5-ene-1,2,3,4-tetrol 
• 156726-58-8 1L-<1(OH),2,3/4>-3,4-Bis-O-(methoxymethyl)-1-(3,4-dimethoxyphenyl)cyclohexane-1,2,3,4-tetrol 
• 156487-75-1 (3R,4R)-3,4-Bis(methoxymethoxy)-1-(3,4-dimethoxyphenyl)-cyclohexene 
• 80245-51-8 4-lithio-1,2-dimethoxybenzene 
• 187277-52-7 Acetic acid (1S,6R)-3-(3,4-dimethoxy-phenyl)-6-methoxymethoxy-cyclohex-2-enyl ester 
• 187277-51-6 Acetic acid (1R,6R)-3-(3,4-dimethoxy-phenyl)-6-methoxymethoxy-cyclohex-2-enyl ester 
• 156558-40-6 (3S,4R)-1-(3,4-Dimethoxyphenyl)-3-hydroxy-4-(methoxymethoxy)cyclohexene 
• 156487-78-4 Ethyl <(1R,4R)-1-(3,4-dimethoxyphenyl)-4-(methoxymethoxy)cyclohex-2-enyl>acetate 
• 156487-80-8 N-<2-<(1R,4R)-1-(3,4-Dimethoxyphenyl)-4-(methoxymethoxy)cyclohex-2-enyl>>ethyl-N-methylamine 
• 156487-79-5 2-<(1R,4R)-1-(3,4-Dimethoxyphenyl)-4-(methoxymethoxy)cyclohex-2-enyl>ethanal 
• 156487-81-9 O-Methoxymethyl mesembranol 

Downstream Products

• 468-53-1 (-)-mesembrine 
• 58117-98-9 mesembranol methiodide 

Relevant academic research and scientific papers

Chiral and stereoselective total synthesis of (-)-mesembranol starting from D-glucose

A chiral synthesis of the Sceletium alkaloid (-)-mesembranol 1 is described. The cyclohexane ring in 1 is prepared in an optically active form from D-glucose using Ferrier's carbocyclisation, and the critical stereochemistry of the quaternary carbon in 1 is constructed stereoselectively via chirality transfer by way of Claisen rearrangement of the cyclohexenol derivative 14a. The perhydroindole skeleton in 1 is effectively generated by intramolecular aminomercuriation of the amino-olefin 18.

Chiral synthesis of (-)-mesembranol starting from D-glucose

The chiral synthesis of the Sceletium alkaloid, (-)-mesembranol 1 is described; the cyclohexane ring in 1 is prepared in an optically active form from D-glucose using Ferrier's carbocyclisation reaction and the perhydroindole skeleton is effectively constructed by an intramolecular aminomercuration reaction.