23549-54-4Relevant articles and documents
HYDROLYSIS OF BARBITURIC ACID DERIVATIVES.PART IV. HYDROLYSIS OF DERIVATIVES WITHOUT SHIELDING STERIC EFFECT
Mokrosz, Jerzy,Bojarski, Jacek
, p. 491 - 500 (2007/10/02)
Kinetics and products of hydrolysis of the monoanion form of three C-5 spirobarbiturates with 4-, 5- and 6-membered rings and 5,5-dimethylbarbituric acid have been investigated.The pKa values of these compounds were determined and the analysis of C=O stretching modes has been carried out.The effects of substituents at the C-5 carbon atom of barbituric acids on the rates of hydrolysis are discussed.