23574-78-9Relevant academic research and scientific papers
Room-temperature palladium-catalyzed coupling of heteroaryl amines with aryl or heteroaryl bromides
Moss, Thomas A.,Addie, Matthew S.,Nowak, Thorsten,Waring, Michael J.
, p. 285 - 289 (2012)
Heteroaryl amines readily undergo Buchwald-Hartwig amination reactions with a range of aryl and heteroaryl bromides at room temperature using t-BuXPhos Pd-precatalyst and NaOt-Bu. The pharmaceutically attractive biaryl amines are generally formed in short reaction times (0.5-16 h) and in good to excellent yields. Georg Thieme Verlag Stuttgart - New York.
