235783-18-3Relevant articles and documents
CuCl2-Mediated Oxidative Intramolecular α-Arylation of Ketones with Phenolic Nucleophiles via Oxy-Allyl Cation Intermediates
Aota, Yusuke,Kano, Taichi,Maruoka, Keiji,Mochimatsu, Takuto
supporting information, p. 3816 - 3819 (2020/10/19)
α-Functionalization of ketones in an umpolung fashion can be achieved by nucleophilic addition to the oxy-allyl cation intermediate. However, applicable carbon nucleophiles are limited to ones with high nucleophilicity. Additionally, introduction of a lea
Hypervalent iodine(III)-induced intramolecular cyclization of α-(aryl)alkyl-β-dicarbonyl compounds: A convenient synthesis of benzannulated and spirobenzannulated compounds
Arisawa,Ramesh,Nakajima,Tohma,Kita
, p. 59 - 65 (2007/10/03)
A novel hypervalent iodine(III)-induced direct intramolecular cyclization of α-(aryl)alkyl-β-dicarbonyl compounds has been described. Both meta- and para-substituted phenol ether derivatives containing acyclic or cyclic 1,3-dicarbonyl moieties at the side chain undergo this reaction in a facile manner. The reactions afford benzannulated and spirobenzannulated compounds that are of biological importance. The reaction is found to be general, mild, and high yielding. The mechanism of the reaction has been shown to involve a cation radical intermediate.