236111-74-3

Upstream product

• 610-78-6 3-nitro-4-chlorophenol 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1076222-87-1 [3-(3-bromo-phenoxymethyl)-phenyl]-(7-methyl-pyrido[2,3-d]pyrimidin-4-yl)-amine trifluoroacetate 
• 943620-82-4 4-[2-amino-4-(4-methoxy-benzyloxy)-phenylsulfanyl]-phenol 
• 943620-81-3 4-[4-(4-methoxy-benzyloxy)-2-nitro-phenylsulfanyl]-phenol 
• 236111-76-5 N-<2-(1-azabicyclo<3.3.0>octan-2-one-5-yl)ethyl>-4-(4-methoxybenzyloxy)-2-nitroaniline 
• 236111-77-6 N-<2-(1-azabicyclo<3.3.0>octan-2-on-5-yl)ethyl>-4-hydroxy-2-nitroaniline 
• 920982-72-5 [9-(3,5-bis-trifluoromethyl-benzenesulfonyl)-6-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-74-7 [9-(biphenyl-4-sulfonyl)-6-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-78-1 [9-(biphenyl-4-sulfonyl)-8-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-75-8 [9-(2-bromo-benzenesulfonyl)-6-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-76-9 [9-(4-chloro-benzenesulfonyl)-8-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-73-6 [9-(4-chloro-benzenesulfonyl)-6-methoxy-9H-carbazol-2-yloxy]-acetic acid tert-butyl ester 
• 920982-66-7 6-methoxy-2-(4-methoxy-benzyloxy)-9H-carbazole 
• 920982-67-8 1-methoxy-7-(4-methoxy-benzyloxy)-9H-carbazole 
• 920982-65-6 3'-methoxy-4-(4-methoxy-benzyloxy)-2-nitro-biphenyl 

Relevant academic research and scientific papers

Synthesis and biological activity of the metabolites of N-[2-(1- azabicyclo[3.3.0]octan-5-yl)ethyl]-2-nitroaniline Fumarate (SK-946)

Three metabolites of N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-2- nitroaniline fumarate (SK-946), a novel central muscarinic cholinergic receptor agonist, were prepared to confirm their proposed structures, and tested for muscarinic receptor affinity in vitro.

N-Substituted carbazolyloxyacetic acids modulate Alzheimer associated γ-secretase

N-Sulfonylated and N-alkylated carbazolyloxyacetic acids were investigated for the inhibition and modulation of the Alzheimer's disease associated γ-secretase. The introduction of a lipophilic substituent, which may vary from arylsulfone to alkyl, turned

ANTI-VIRAL COMPOUNDS

Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

ANTI-VIRAL COMPOUNDS

Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.