236117-38-7

Usage

Uses

Used in Organic Synthesis:
1-Propanone, 2-iodo-1-(4-methylphenyl)is used as a reagent in organic synthesis for its unique chemical properties, enabling the creation of a variety of complex organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-Propanone, 2-iodo-1-(4-methylphenyl)serves as an intermediate in the development of new drugs, leveraging its specific structure to contribute to the synthesis of potential medicinal compounds.
Used in the Development of Fine Chemicals:
1-Propanone, 2-iodo-1-(4-methylphenyl)is also utilized in the production of fine chemicals, where its unique properties can be harnessed to create high-quality specialty products for various applications.

Upstream product

• 5337-93-9 4'-methylpropiophenone 
• 874-60-2 4-methyl-benzoyl chloride 
• 74-88-4 methyl iodide 
• 92821-88-0 2-bromo-4'-methylpropiophenone 

Relevant academic research and scientific papers

α,α-Alkylation-Halogenation and Dihalogenation of Sulfoxonium Ylides. A Direct Preparation of Geminal Difunctionalized Ketones

A one-pot alkylation–halogenation of ketosulfoxonium ylides in the presence of alkyl halides is described. The method furnishes several gem-difunctionalized haloketones (an alkyl and F, Cl, Br, or I) in good yields. Replacing alkyl halides with a mixture of electrophilic halogen species and various halide anions led to gem-dihalogenated ketones containing a combination of the same or two different halogens. Kinetic isotopic effects as well as reaction kinetic experiments give insight to the mechanism of these reactions.

Efficient α-iodination of carbonyl compounds under solvent-free conditions using microwave irradiation

Direct conversion of carbonyl compounds into α-iodocarbonyl compounds has been successfully achieved under solvent-free microwave irradiation conditions using N-iodosuccinimide and p-toluenesulfonic acid.

Efficient method for α-iodination of ketones

α-Iodoketones are prepared in high yields from the initial reaction of various ketones with HNIB in CH3CN and subsequent treatment of potassium iodide or samarium(II) iodide.