23612-33-1

Basic information

• Product Name: 3-NITRO-4-AZAINDOLE
• Synonyms: 3-NITRO-4-AZAINDOLE;3-Nitro-1H-pyrrolo[3,2-b]pyridine
• CAS NO: 23612-33-1
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.135
• Mol File: 23612-33-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 386.17°C at 760 mmHg
• Flash Point: 187.349°C
• Appearance: /
• Density: 1.525g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.741
• Storage Temp.: 2-8°C
• PKA: 11.62±0.40(Predicted)
• CAS DataBase Reference: 3-NITRO-4-AZAINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-NITRO-4-AZAINDOLE(23612-33-1)
• EPA Substance Registry System: 3-NITRO-4-AZAINDOLE(23612-33-1)

Safety Data

• Hazardous Substances Data: 23612-33-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H5N3O2/c11-10(12)6-4-9-5-2-1-3-8-7(5)6/h1-4,9H

Upstream product

• 272-49-1 1H-pyrrolo[3,2-b]pyridine 

Downstream Products

• 1092960-98-9 1H-pyrrolo[3,2-b]pyridin-3-amine 

Relevant articles and documents

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that inhibit (e.g., antagonize) Stimulator of Interferon Genes (STING). Said chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) STING activation (e.g., STING signaling) contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions containing the same as well as methods of using and making the same.

ALKYL-SUBSTITUTED 3' COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, Ar, m and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.