236121-55-4Relevant academic research and scientific papers
Novel perfluoroacyl olefinations of aldehydes using β-thio-substituted perfluoroalkyl enol ethers
Yoshimatsu, Mitsuhiro,Sugimoto, Tomomi,Okada, Naoyuki,Kinoshita, Sayaka
, p. 5162 - 5165 (2007/10/03)
α-(Methylthio)- or α-(phenylthio)-substituted perfluoroacylolefinations of nonenolizable aldehydes using the β-lithio-β- thio-perfluoroalkyl enol ethers 1-4 stereoselectively proceeded to give (Z)- α,β-unsaturated perfluoroalkyl ketones 9a-e, 10a-c, 11a-c, and 12a. The α- (thio)-α,β-unsaturated trifluoromethyl ketones were easily converted to 3- (thio)-2-(trifluoromethyl)-1,3-butadienes 21a-c and 22a,b in moderate to high yields (41-85%).
