23622-20-0Relevant academic research and scientific papers
Structure-based design of rhodanine-based acylsulfonamide derivatives as antagonists of the anti-apoptotic Bcl-2 protein
Li, Huan-Qiu,Yang, Jing,Ma, Shuhua,Qiao, Chunhua
experimental part, p. 4194 - 4200 (2012/08/28)
A series of novel rhodanine-based acylsulfonamide derivatives were designed, synthesized, and evaluated as small-molecule inhibitors of anti-apoptotic Bcl-2 protein. These compounds exhibit potent antiproliferative activity in three human tumor cell lines
Synthesis and characterization of (Z)-5-arylmethylidenerhodanines with photosynthesis-inhibiting properties
Opletalova, Veronika,Dolezel, Jan,Kralova, Katarina,Pesko, Matus,Kunes, Jiri,Jampilek, Josef
experimental part, p. 5207 - 5227 (2011/08/06)
A series of rhodanine derivatives was prepared. The synthetic approach, analytical and spectroscopic data of all synthesized compounds are presented. Lipophilicity of all the discussed rhodanine derivatives was analyzed using the RP-HPLC method. The compo
COMPOUNDS USEFUL AS HYPOGLYCEMIC AGENTS AND FOR TREATING ALZHEIMER'S DISEASE
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, (2008/06/13)
Provided are methods for treating hyperglycemia and Alzheimer's disease utilizing certain rhodanine derivatives. Certain of the rhodanine derivatives utilized in the instant methods are novel and, accordingly, such compounds and pharmaceutical formulation
