236386-38-2

Upstream product

• 223600-53-1 1-((S)-1-Hydroxymethyl-2-phenyl-ethyl)-3-phenyl-urea 
• 254900-22-6 1-((S)-1-Hydroxymethyl-2-phenyl-ethyl)-3-phenyl-thiourea 
• 3182-95-4 L-Phenylalaninol 
• 103-71-9 phenyl isocyanate 

Relevant academic research and scientific papers

A mild cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas to 2-phenylamino-2-oxazolines using TsCl/NaOH

An efficient synthesis of 2-phenylamino-2-oxazolines 3 via cyclodesulfurization of N-(2-hydroxyethyl)-N′-phenylthioureas 2 by a one-pot reaction using p-toluenesulfonyl chloride (TsCl) and NaOH in very good yields is described.

Investigation of the Mitsunobu reaction of N-(2-hydroxyethyl)-N'- phenyl-ureas

The Mitsunobu reaction of N-(2-hydroxyethyl)-ureas 1 using PPh3 and EtO2CN=NCO2Et led to the mixture of N- and O-alkylation products or a single isomer depending on the substrates.