236401-60-8

Upstream product

• 75-07-0 acetaldehyde 
• 160666-92-2 (S)-2-benzoyloxypentan-3-one 

Downstream Products

• 236401-75-5 (2S,4R,5R)-5-((4-methoxybenzyl)oxy)-4-methyl-3?oxohexan-2-yl benzoate 
• 236401-74-4 (2S,4S,5R)-5-(4-methoxybenzyloxy)-4-methylhexan-2,3-diol 
• 236401-72-2 (2R,3R,4S,5S,6R,7R)-7-(4-methoxybenzyloxy)-3,5-isopropylidenedioxy-2,4,6-trimethyloctan-1-al 
• 236401-70-0 (2S,3S,4R,5S,6R,7R)-7-(4-methoxybenzyloxy)-3,5-isopropylidenedioxy-2,4,6-trimethyloctan-1-ol 
• 236401-62-0 (2S,3S,4R,5S,6R,7R)-1-benzyloxy-7-(4-methoxybenzyloxy)-3,5-isopropylidenedioxy-2,4,6-trimethyloctane 
• 236401-77-7 (2S,3S,4R,5R,6S,7R)-1-benzyloxy-7-(4-methoxybenzyloxy)-2,4,6-trimethyl-3,5-octandiol 
• 236401-63-1 (2S,4S,5S,6S,7R)-1-benzyloxy-5-hydroxy-7-(4-methoxybenzyloxy)-2,4,6-trimethyloctan-3-one 

Relevant academic research and scientific papers

Synthesis of the C(7)-C(20) fragment of spirotoamides A, B and C

This work describes the preparation of the C(7)-C(20) fragment of spirotoamides A to C in a very elegant fashion, achievement very high levels of stereocontrol. The synthesis has been accomplished by a sequence involving 14 steps (0.36percent overall yiel

Stereoselective synthesis of fully functionalized acyclic core of Tianchimycin A

A highly convergent synthetic approach towards the macrolactone polyketide tianchimycin A is described. Notable features of our synthetic approach include highly stereoselective Myers alkylation, substrate controlled anti aldol reaction, and Masamune-Roush olefination.

Total synthesis of elaiolide using a copper(l)-promoted stille cyclodimerization reaction

(equation presented) Elaiolide (2) The 16-membered macrodiolide elaiolide (2) has been prepared in 20 steps from the ketone (S)-8 in 9.3% overall yield with a diastereoselectivity of 76%. Key steps included the copper(l) thiophene-2-carboxylate promoted c