23647-78-1

Basic information

• Product Name: disalicylohydrazide
• Synonyms: disalicylohydrazide;N,N'-bis(salicyl)hydrazine;1,2-Bis(2-hydroxybenzoyl)hydrazine;NSC-408200
• CAS NO: 23647-78-1
• Molecular Formula: C₁₄H₁₂N₂O₄
• Molecular Weight: 302.28536
• EINECS: 245-804-4
• Mol File: 23647-78-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 595.7°Cat760mmHg
• Flash Point: 314.1°C
• Appearance: /
• Density: 1.397g/cm³
• Vapor Pressure: 8.67E-15mmHg at 25°C
• Refractive Index: 1.663
• CAS DataBase Reference: disalicylohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: disalicylohydrazide(23647-78-1)
• EPA Substance Registry System: disalicylohydrazide(23647-78-1)

Safety Data

• Hazardous Substances Data: 23647-78-1(Hazardous Substances Data)

Usage

General Description

Disalicylohydrazide is a chemical compound with the molecular formula C13H12N2O4. It is a white to off-white crystalline powder and is known for its ability to chelate metal ions, particularly iron, copper, and zinc. Disalicylohydrazide has found applications in various industries, including pharmaceuticals, dyes, and cosmetics, due to its metal chelating properties. It is also used as an antioxidant in rubber and plastics. Additionally, disalicylohydrazide has been studied for its potential antiviral and antibacterial properties, making it a promising candidate for further research in the field of medicine and biotechnology.

InChI:InChI=1/C14H12N2O4/c17-11-7-3-1-5-9(11)13(19)15-16-14(20)10-6-2-4-8-12(10)18/h1-8,17-18H,(H,15,19)(H,16,20)

Upstream product

• 936-02-7 2-Hydroxybenzoylhydrazine 
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• 64-19-7 acetic acid 
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Downstream Products

• 2491-96-5 2,5-bis(2-hydroxyphenyl)-1,3,4-oxadiazole 

Relevant articles and documents

Synthesis, structure, characterization and study of antiproliferative activity of dimeric and tetrameric oxidomolybdenum(VI) complexes of N,N′-disalicyloylhydrazine

The in situ reaction of salicyloylhydrazide and its corresponding hydrazone with [MoO2(acac)2] afforded two novel and unusual dimeric [(MoVIO2)2L] (1) and tetrameric [{(C 2H5OH)LO3Mo2VI} 2(μ-O)2]·C2H5OH (2) oxidomolybdenum(VI) complexes with N,N′-disalicyloylhydrazine (H 2L). The binucleating ligand was formed by the self-combination of the acid hydrazide or corresponding hydrazone. The complexes were characterized by various spectroscopic techniques (IR, UV and NMR) and also by electrochemical study. The molecular structures of both complexes have been confirmed by X-ray crystallography. The above studies indicate that the N,N′- disalicyloylhydrazine (H2L) has the normal tendency to form both dimeric and tetrameric complexes coordinated through the dianionic tridentate manner. The in vitro antiproliferative activity of complexes 1 and 2 was assayed against HeLa cell line.

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COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS

The present invention relates to derivatives of the 1H-pyrano[4,3-b]benzofuran-1-one structure and their nitrogen analogues which possess powerful antioxidant properties combined with a highly effective UV absorbing functionality in one molecule. These compounds are especially useful in cosmetical and dermatological formulations.