23651-95-8 Usage
Uses
Used in Pharmaceutical Industry:
Droxidopa is used as an antiparkinsonian agent for improving symptoms such as retropulsion, dysarthria, and muscular rigidity in Parkinsonian patients when added to existing levodopa/decarboxylase inhibitor therapy.
Used in Neurological Treatment:
Droxidopa is used as a treatment for neurogenic orthostatic hypotension, as it increases norepinephrine levels in the brain and helps improve blood pressure regulation.
Used in Clinical Trial Studies:
L-DOPS has been administered in clinical trial studies for mice with amyloid pathology, as it mediates the reduction of amyloid plaques and could have therapeutic potential for treating amyloid-related conditions.
Used in Drug Development:
Droxidopa is used as a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline), with potential applications in the development of new medications for various neurological and psychiatric disorders.
Originator
Sumitomo (Japan)
Biochem/physiol Actions
L-DOPS is a norepinephrine precursor in vivo.
Check Digit Verification of cas no
The CAS Registry Mumber 23651-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,6,5 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23651-95:
(7*2)+(6*3)+(5*6)+(4*5)+(3*1)+(2*9)+(1*5)=108
108 % 10 = 8
So 23651-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8-/m0/s1
