23652-87-1Relevant academic research and scientific papers
INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS
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Page/Page column 297; 298, (2021/01/29)
The present invention is directed to indazole and azaindazole compounds which are inhibitors of LRRK2 and are useful in the treatment of CNS disorders.
Photosynthetic Electron Transport Inhibition By Pyrones and Pyridones: Structure-Activity Relationship
Asami, Tadao,Yoshida, Shigeo,Takahashi, Nobutaka
, p. 469 - 474 (2007/10/02)
The 4-pyrone and 4-pyridone series were examined as a new typ of photosynthetic inhibitor because of a structural resemblance to the co-enzyme plastoquinone, which lies between photosystem II and cytochrome b.These compounds inhibited a Hill reaction at "the plastoquinone pool". From our study of the structure/activity relationships for 4-pyrones and 4-pyridones, it has become clear that these compounds need no strict structural resemblance to the plastoquinone.It is also demonstrated that the brominated 4-pyridone series has remarkably higher inhibitory activities than those of its non brominated analogues.
