23668-03-3Relevant academic research and scientific papers
Suzuki cross-coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4-methoxy-6-methyl-2-pyrones
Marrison, Lester R.,Dickinson, Julia M.,Fairlamb, Ian J.S.
, p. 2667 - 2671 (2003)
Suzuki cross-coupling has been used to access a wide range of 3- and 5-substituted 2-pyrones, which show remarkable inhibitory activity against bacteria, yeasts and fungi. 3-Octenyl and 5-octenyl 2-pyrones inhibit human ovarium carcinoma (A2780) and human chronic myelogenous leukaemia (K562) cell lines at the micromolar level.
Regeneration of the carbonyl group in the hypervalent iodine oxidation of carbonyl derivatives of dehydroacetic acid and its analogues
Pundeer, Rashmi,Chaudhri, Vishwas,Kinger, Mayank,Prakash, Om
, p. 834 - 837 (2008/09/18)
Hypervalent iodine oxidation of carbonyl derivatives of dehydroacetic acid and its analogues leads to a mild and efficient regeneration of parent carbonyl compounds leaving pyrone moiety intact.
Synthesis of 3β,3β,5-tribromoacetyl-4-hydroxy-6-methyl-2H-pyran- 2-one by bromination of dehydroacetic acid
Kumar, Ajay,Prakash, Richa,Singh, Shiv P.
, p. 461 - 464 (2007/10/03)
Bromination of dehydroacetic acid giving rise to 3β,3β,5- tribromoacetyl-4-hydroxy-6-methyl-2H-pyran-2-one is described. Copyright Taylor & Francis, Inc.
