236745-80-5Relevant academic research and scientific papers
Enantiodivergent total syntheses of (+)- and (-)-scopadulcic acid A
Fox, Martin E.,Li, Chi,Marino Jr., Joseph P.,Overman, Larry E.
, p. 5467 - 5480 (1999)
The first enantioselective total synthesis of scopadulcic acid A is described. The key step is a cascade intramolecular Heck reaction of a methylenecycloheptene iodide, which generates the B, C, and D rings of the scopadulan ring system in 90% yield as a
