236752-43-5

Basic information

• Product Name: 5-hydroxymethyl-2-phenyl-5-phthalimidomethyl-1,3-dioxane
• Synonyms: 5-hydroxymethyl-2-phenyl-5-phthalimidomethyl-1,3-dioxane
• CAS NO: 236752-43-5
• Molecular Weight: 353.375
• Mol File: 236752-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-hydroxymethyl-2-phenyl-5-phthalimidomethyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxymethyl-2-phenyl-5-phthalimidomethyl-1,3-dioxane(236752-43-5)
• EPA Substance Registry System: 5-hydroxymethyl-2-phenyl-5-phthalimidomethyl-1,3-dioxane(236752-43-5)

Safety Data

• Hazardous Substances Data: 236752-43-5(Hazardous Substances Data)

Upstream product

• 136918-14-4 phthalimide 
• 2425-41-4 5,5-dihydroxymethyl-2-phenyl-1,3-dioxane 

Downstream Products

• 236752-49-1 2-phenyl-5-phthalimidomethyl-1,3-dioxane-5-carboxylic acid 

Relevant articles and documents

Synthesis of achiral α,α-disubstituted β-alanines, and their use in construction of libraries of β-peptide conjugates of N-2-alkyl-1,2,3,4- tetrahydroisoquinolines on a solid support

Six achiral N-phthaloyl protected α,α-disubstituted β-amino acids were synthesized, and used to construct a 96 compound library of 1,2,3,4- tetrahydroisoquinoline conjugates of β-peptides on a solid support. The library synthesis consisted of attachment of an appropriately 5-O-tethered 1,2,3,4-tetrahydroisoquinoline via the N-2 atom to a vinyl sulfonyl support, elongation of the deprotected 5-O-tether by repeated peptide coupling, quaternarization of N-2 with alkylamines and release of the β-peptide conjugate into solution with triethylamine.