2369-74-6

Basic information

• Product Name: 3,4'-bis(trifluoromethyl)-1,1'-biphenyl
• Synonyms: 3,4'-bis(trifluoromethyl)-1,1'-biphenyl
• CAS NO: 2369-74-6
• Molecular Weight: 290.208
• Mol File: 2369-74-6.mol

Chemical Properties

• CAS DataBase Reference: 3,4'-bis(trifluoromethyl)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4'-bis(trifluoromethyl)-1,1'-biphenyl(2369-74-6)
• EPA Substance Registry System: 3,4'-bis(trifluoromethyl)-1,1'-biphenyl(2369-74-6)

Safety Data

• Hazardous Substances Data: 2369-74-6(Hazardous Substances Data)

Upstream product

• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 98-08-8 α,α,α-trifluorotoluene 

Relevant articles and documents

Nickel/magnesium-lanthanum mixed oxide catalyst in the Kumada-coupling

A new, heterogeneous, magnesium-lanthanum mixed oxide solid base-supported nickel(ii) catalyst was developed. The catalyst was used successfully in the Kumada coupling of aryl halides, especially aryl bromides. The optimal reaction conditions of the coupling were determined.

Palladium(II)-catalyzed coupling of electron-deficient arenes via C-H activation

Homocoupling and cross-coupling of electron-deficient arenes, including nitrobenzene, (trifluoromethyl)benzene, ethyl benzoate, etc., have been developed to afford biaryls using a catalytic system of Pd(OAc) 2/trifluoroacetic acid (TFA)/O2 or K2S 2O8. The crucial step is to tune the concentrations of arenes and the loading of TFA carefully to enhance the reaction rates and the selectivity of these couplings involving dual C-H activation.