23693-78-9

Basic information

• Product Name: [2-Phenyl-1-[[(phenylmethoxy)carbonyl]amino]-ethyl]phosphonic acid
• Synonyms: [2-Phenyl-1-[[(phenylmethoxy)carbonyl]amino]-ethyl]phosphonic acid
• CAS NO: 23693-78-9
• Molecular Weight: 335.296
• Mol File: 23693-78-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [2-Phenyl-1-[[(phenylmethoxy)carbonyl]amino]-ethyl]phosphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [2-Phenyl-1-[[(phenylmethoxy)carbonyl]amino]-ethyl]phosphonic acid(23693-78-9)
• EPA Substance Registry System: [2-Phenyl-1-[[(phenylmethoxy)carbonyl]amino]-ethyl]phosphonic acid(23693-78-9)

Safety Data

• Hazardous Substances Data: 23693-78-9(Hazardous Substances Data)

Upstream product

• 84690-42-6 dimethyl 1-benzyloxycarbonylamino-2-phenylethyl phosphonate 
• 14332-09-3 hypophosphorous acid 
• 67532-87-0 Phenylacetyl-phosphonic acid dibenzyl ester 

Downstream Products

• 153465-23-7 Benzyl (+/-)-<1-<(benzyloxycarbonyl)amino>-2-phenylethyl>phosphonic acid 

Relevant articles and documents

A mild and convenient oxidation of H-phosphinic acids

A new mild and convenient method of oxidation of H-phosphinic to the corresponding phosphonic acids was developed. Conversion of H-phosphinic acids into trivalent trimethylsilyl esters using hexamethyldisilazane, followed by their oxidation with air and subsequent methanolysis allowed obtaining the final compounds in good to excellent yields. The methodology was proved to be particularly useful for N-benzyloxycarbonyl-α-aminophosphinic acids. The scope and limitations of the reaction were additionally tested using a variety of both free and protected amino- and hydroxyphosphinates as substrates.

Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors

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