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2-METHYL-3-NITROPHENYL ISOCYANATE, with the chemical formula C8H6N2O3, is a yellowish powder that is highly reactive. It is a potent irritant to the skin, eyes, and respiratory system, and is classified as a hazardous material due to its toxic and flammable properties. As a potential allergen and sensitizer, it can cause allergic reactions in some individuals. It is used in the production of various polymers and pharmaceuticals, and should be handled with extreme caution.

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  • 23695-15-0 Structure
  • Basic information

    1. Product Name: 2-METHYL-3-NITROPHENYL ISOCYANATE
    2. Synonyms: 2-METHYL-3-NITROPHENYL ISOCYANATE;1-isocyanato-2-methyl-3-nitrobenzene;1-isocyanato-2-methyl-3-nitrobenzene(SALTDATA: FREE);478350_ALDRICH;ZINC02384725
    3. CAS NO:23695-15-0
    4. Molecular Formula: C8H6N2O3
    5. Molecular Weight: 178.14
    6. EINECS: N/A
    7. Product Categories: Isocyanates;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
    8. Mol File: 23695-15-0.mol
  • Chemical Properties

    1. Melting Point: 34-37°C
    2. Boiling Point: 118°C 2,8mm
    3. Flash Point: >110°C
    4. Appearance: /
    5. Density: 1.4114 (rough estimate)
    6. Vapor Pressure: 0.00425mmHg at 25°C
    7. Refractive Index: 1.6000 (estimate)
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. Sensitive: Moisture Sensitive
    11. BRN: 9120119
    12. CAS DataBase Reference: 2-METHYL-3-NITROPHENYL ISOCYANATE(CAS DataBase Reference)
    13. NIST Chemistry Reference: 2-METHYL-3-NITROPHENYL ISOCYANATE(23695-15-0)
    14. EPA Substance Registry System: 2-METHYL-3-NITROPHENYL ISOCYANATE(23695-15-0)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 20/21/22-36/37/38-42
    3. Safety Statements: 22-26-36/37/39-36
    4. RIDADR: 2206
    5. WGK Germany:
    6. RTECS:
    7. HazardClass: 6.1
    8. PackingGroup: III
    9. Hazardous Substances Data: 23695-15-0(Hazardous Substances Data)

23695-15-0 Usage

Uses

Used in Polymer Production:
2-METHYL-3-NITROPHENYL ISOCYANATE is used as a monomer in the production of various polymers. Its high reactivity allows it to form strong covalent bonds with other molecules, resulting in the creation of polymers with unique properties.
Used in Pharmaceutical Industry:
2-METHYL-3-NITROPHENYL ISOCYANATE is used as a chemical intermediate in the synthesis of pharmaceuticals. Its reactive nature enables it to be incorporated into the structure of various drug molecules, potentially enhancing their therapeutic effects.
Used in Research and Development:
2-METHYL-3-NITROPHENYL ISOCYANATE is used as a research chemical in the development of new materials and compounds. Its unique properties and reactivity make it a valuable tool for scientists and researchers in various fields, including chemistry, materials science, and pharmaceuticals.

Check Digit Verification of cas no

The CAS Registry Mumber 23695-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,6,9 and 5 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23695-15:
(7*2)+(6*3)+(5*6)+(4*9)+(3*5)+(2*1)+(1*5)=120
120 % 10 = 0
So 23695-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N2O3/c1-6-7(9-5-11)3-2-4-8(6)10(12)13/h2-4H,1H3

23695-15-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (L10636)  2-Methyl-3-nitrophenyl isocyanate, 98%   

  • 23695-15-0

  • 1g

  • 213.0CNY

  • Detail
  • Alfa Aesar

  • (L10636)  2-Methyl-3-nitrophenyl isocyanate, 98%   

  • 23695-15-0

  • 5g

  • 916.0CNY

  • Detail
  • Aldrich

  • (478350)  2-Methyl-3-nitrophenylisocyanate  98%

  • 23695-15-0

  • 478350-2G

  • 808.47CNY

  • Detail

23695-15-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Isocyanato-2-methyl-3-nitrobenzene

1.2 Other means of identification

Product number -
Other names 2-methyl-3-nitrobenzenisocyanate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23695-15-0 SDS

23695-15-0Downstream Products

23695-15-0Relevant articles and documents

MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE

-

Paragraph 0781; 0782; 0781; 0790, (2017/09/20)

Provided herein are maytansinoid compounds, derivatives thereof, conjugates thereof, and methods of treating or preventing proliferative diseases with the same.

A simple and efficient synthesis of diaryl ureas with reduction of the intermediate isocyanate by triethylamine

Zhou, Shuguang,Yao, Ting,Yi, Jicheng,Li, Dashuai,Xiong, Jing

, p. 315 - 319 (2013/07/27)

Thirty symmetrical diaryl urea derivatives were synthesised in moderate to excellent yields from arylamine and triphosgene with triethylamine as a reducing agent for the intermediate, isocyanate. It was significant that part of the products could be collected in almost quantitative yield without column chromatography. The procedure under mild reaction conditions was tolerant of a wide range of functional groups. The structures of the compounds were determined by NMR, MS and X-ray crystallographic analyses.

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