237056-75-6Relevant academic research and scientific papers
Synthesis and cytotoxic evaluation of combretastatin A-4 analogues of benzo[b]furans
Fan, Ye,Luo, Yang,Ma, Cheng
, p. 1823 - 1832 (2017)
Abstract: A series of benzo[b]furans was synthesized with modification at the 5-position of the benzene ring by introducing different aryl acetylenyl and acrylic acid moiety as combretastatin A-4 analogues. The compounds were evaluated by MTT assay for cy
Fluorescent 2-(2′-hydroxybenzofuran)benzoxazole (HBBO) borate complexes: Synthesis, optical properties, and theoretical calculations
Massue, Julien,Benelhadj, Karima,Chibani, Siwar,Le Guennic, Boris,Jacquemin, Denis,Retailleau, Pascal,Ulrich, Gilles,Ziessel, Raymond
, p. 4136 - 4140 (2014/07/22)
The multi-step synthesis, structural and optical properties of original luminescent borate complexes derived from 2-(2′-hydroxybenzofuran) benzoxazole (HBBO) are reported. Functionalization at position 3 of the benzofuran ring was readily achieved through an electrophilic cyclization key step followed by a Sonogashira cross-coupling reaction. The optical properties of the resulting boron difluoride dyes highlight different photophysical behaviors depending on the nature of the substitution at position 3 of the benzofuran core (tBu-phenylacetylene or NnBu 2-phenylacetylene). The NnBu2-phenylacetylene moiety favors a sizeable intramolecular charge transfer as evidenced by a strong solvatochromism; a feature further confirmed by ab initio calculations.
Synthesis of luminescent ethynyl-extended regioisomers of borate complexes based on 2-(2′-hydroxyphenyl)benzoxazole
Massue, Julien,Frath, Denis,Retailleau, Pascal,Ulrich, Gilles,Ziessel, Raymond
supporting information, p. 5375 - 5386 (2013/05/21)
A series of thirteen luminescent tetrahedral borate complexes based on the 2-(2′-hydroxyphenyl)benzoxazole (HBO) core is presented. Their synthesis includes the incorporation of an ethynyl fragment by Sonogashira cross-coupling reaction, with the goal of
Synthesis of 8-aryl-substituted coumarins based on ring-closing metathesis and Suzuki-Miyaura coupling: Synthesis of a furyl coumarin natural product from Galipea panamensis
Schmidt, Bernd,Krehl, Stefan,Kelling, Alexandra,Schilde, Uwe
supporting information; experimental part, p. 2360 - 2367 (2012/05/31)
The synthesis of 7-methoxy-8-(4-methyl-3-furyl)-2H-chromen-2-one, a natural product with antileishmanial activity recently isolated from the plant Galipea panamensis, is described. The key step is a Suzuki-Miyaura coupling of a furan-3-boronic acid and an
