23713-93-1Relevant academic research and scientific papers
Copper(II)-mediated O-arylation of protected serines and threonines
El Khatib, Mirna,Molander, Gary A.
, p. 4944 - 4947 (2014)
An effective protocol toward the O-arylation of β-hydroxy-α-amino acid substrates serine and threonine has been developed via Chan-Lam cross-coupling. This Cu(II)-catalyzed transformation involves benign open-flask conditions that are welltolerated with a variety of protected (Boc-, Cbz-, Tr-, and Fmoc-) serine and threonine derivatives and various potassium organotrifluoroborates and boronic acids.
Reductive Cleavage of C—O Bond in Model Compounds of Lignin
Xu, Huanjun,Liu, Xinwei,Zhao, Yanfei,Wu, Cailing,Chen, Yu,Gao, Xiang,Liu, Zhimin
, p. 938 - 942 (2017/06/28)
A simple protocol for reductive cleavage of C—O bond in diaryl and aryl methyl ethers was reported, in which NaH served as a reducing agent and KOtBu as a base and a radical initiator. The combination of NaH and KOtBu displayed high efficiency for reductive cleavage of C—O bond in diaryl and aryl ethers (e.g., dibenzofuran, diphenyl ether, anisole) without the hydrogenation of the aryl rings, in the absence of any other catalysts or ligands at 140 °C, producing corresponding arenes and phenols. It was indicated that the reaction was under a radical mechanism.
Reductive cleavage of inert aryl C-O bonds to produce arenes
Xu, Huanjun,Yu, Bo,Zhang, Hongye,Zhao, Yanfei,Yang, Zhenzhen,Xu, Jilei,Han, Buxing,Liu, Zhimin
supporting information, p. 12212 - 12215 (2015/07/27)
Reductive cleavage of the aryl C-O bonds in various phenolic compounds and aryl ethers was achieved using LiAlH4 combined with KOtBu and without any other catalysts or additives, solely producing arenes in high yields.
