2372-70-5 Usage
Uses
Used in Pharmaceutical Industry:
ISONIPECOTIC ACID, 1-ALLYL-4-PHENYL-, ETHYL ESTER is used as a chemical intermediate for the development of new drugs and medications. Its unique structure and properties make it a promising candidate for the synthesis of various pharmaceutical compounds.
Used in Organic Synthesis:
In the field of organic synthesis, ISONIPECOTIC ACID, 1-ALLYL-4-PHENYL-, ETHYL ESTER is used as a reagent in chemical reactions. Its versatility allows it to be employed in a wide range of reactions, contributing to the synthesis of various organic compounds.
Used in Research Settings:
Due to its potential applications and unique properties, ISONIPECOTIC ACID, 1-ALLYL-4-PHENYL-, ETHYL ESTER is also used in research settings. Scientists and researchers utilize ISONIPECOTIC ACID, 1-ALLYL-4-PHENYL-, ETHYL ESTER to explore its potential uses and to gain a deeper understanding of its properties and behavior in different chemical environments.
Check Digit Verification of cas no
The CAS Registry Mumber 2372-70-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2372-70:
(6*2)+(5*3)+(4*7)+(3*2)+(2*7)+(1*0)=75
75 % 10 = 5
So 2372-70-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H23NO2/c1-3-12-18-13-10-17(11-14-18,16(19)20-4-2)15-8-6-5-7-9-15/h3,5-9H,1,4,10-14H2,2H3
2372-70-5Relevant academic research and scientific papers
Opioids and efflux transporters. Part 1: P-Glycoprotein substrate activity of N-substituted analogs of meperidine
Mercer, Susan L.,Hassan, Hazem E.,Cunningham, Christopher W.,Eddington, Natalie D.,Coop, Andrew
, p. 1160 - 1162 (2007/10/03)
P-Glycoprotein (P-gp) is an efflux transporter which is up-regulated at the blood-brain barrier in both morphine- and oxycodone-tolerant rats. Numerous studies have shown that many clinically employed opioid analgesics are substrates for P-gp, suggesting that up-regulation of P-gp may contribute to the development of central tolerance to opioids. The studies herein focus on the development of SAR for P-gp substrate activity in the meperidine series of compounds, and show that a meperidine analog of greater potency, N-phenylbutyl-N-normeperidine, has low activity as a P-gp substrate and has the potential to be utilized as a tool to study the contribution of P-gp to the development of central tolerance to opioids.
