237404-30-7Relevant academic research and scientific papers
Synthesis of bicyclic proline analogs using a formal [3+2] intramolecular aziridine-allylsilane cycloaddition reaction
Bergmeier, Stephen C.,Fundy, Susan L.,Seth, Punit P.
, p. 8025 - 8038 (2007/10/03)
Bicyclic proline analogs have a wide range of biological uses. We report here our synthesis of bicyclic proline analogs using a formal [3+2] intramolecular aziridine-allylsilane cycloaddition reaction. This synthesis allows for the preparation of both 5-5 and 6-5 fused ring systems and should be amenable to the preparation of analogs with substitution on the carbocyclic ring.
