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Ethanethioyl chloride, trifluoro-, also known as 2,2,2-trifluoroethanethioyl chloride or trifluoroacetyl chloride, is a chemical compound with the molecular formula C2H2ClF3S. It is a colorless liquid with a pungent odor and is used as a reagent in organic synthesis, particularly for the preparation of trifluoroacetyl derivatives. Ethanethioyl chloride, trifluoro- is highly reactive and can be hazardous, so it should be handled with care, using appropriate safety measures. It is soluble in organic solvents and has a boiling point of 71-72°C. Due to its reactivity, it is commonly used in the pharmaceutical and chemical industries for the synthesis of various compounds, including trifluoroacetylated amino acids, peptides, and other biologically active molecules.

2375-37-3

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2375-37-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2375-37-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2375-37:
(6*2)+(5*3)+(4*7)+(3*5)+(2*3)+(1*7)=83
83 % 10 = 3
So 2375-37-3 is a valid CAS Registry Number.

2375-37-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2,2-trifluoroethanethioyl chloride

1.2 Other means of identification

Product number -
Other names Trifluorthioessigsaeurechlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2375-37-3 SDS

2375-37-3Relevant academic research and scientific papers

Copper-catalyzed three component C[sbnd]S/C[sbnd]N coupling for the synthesis of trifluorothioacetamides

Hu, Bo-Lun,Song, Yi-Kang,Yao, Zengwen,Zhang, Guoqiang,Zhang, Xing-Guo

supporting information, (2020/10/06)

A copper-catalyzed three component C[sbnd]S/C[sbnd]N coupling reaction of imines with sulfur and CFC-113a was developed. The reaction involves amination and C[dbnd]S double bond formation of CFC-113a, leading to biologically important trifluorothioacetamides. The method features efficient construction of trifluorothioacetyl moiety from cheap sulfur and CFC-113a, and safe disposal for environmentally persistent Freon

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