23766-10-1

Upstream product

• 113246-32-5 N-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-N-phenyl-N'-[1-phenyl-meth-(Z)-ylidene]-hydrazine 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 103-71-9 phenyl isocyanate 
• 52185-41-8 benzaldehyde 2-chloroformyl-2-phenylhydrazone 
• 6926-51-8 5-(4-methoxyphenyl)-2H-tetrazole 
• 6926-51-8 5-(4-methoxyphenyl)-1H-tetrazole 
• 4426-68-0 phenyl isoselenocyanate 
• 91759-66-9 2-(4-methoxybenzoyl)-N-phenylhydrazinecarbothioamide 
• 18440-58-9 1-(N-phenylhydrazono)-1-chloropropanone 
• 103-72-0 phenyl isothiocyanate 
• 23766-26-9 5?(4?methoxyphenyl)?1,3,4?oxadiazole?2?thiol 
• 23767-33-1 2-(4-methoxy-phenyl)-5-methylsulfanyl-[1,3,4]oxadiazole 
• 113246-29-0 5-(4-Methoxy-phenyl)-tetrazole-2-carboxylic acid N-phenyl-N'-[1-phenyl-meth-(E)-ylidene]-hydrazide 
• 23767-34-2 2-(p-methoxyphenyl)-5-(methanesulfonyl)-1,3,4-oxadiazole 

Relevant academic research and scientific papers

A KHSO4 mediated facile synthesis of 2-amino-1,3,4-oxadiazole derivatives

A novel, efficient and mild KHSO4 mediated synthesis for 2-amino-1,3,4-oxadiazoles has been established via the cyclodesulfurization of benzoylhydrazine and isothiocyanate derivatives in one pot. The reactions proceeded smoothly at room tempera

Preparation method of 2-amino-1, 3, 4-oxadiazole compound and prepared compound

The invention belongs to the field of medical chemistry, and particularly relates to a preparation method of a 2-amino-1, 3, 4-oxadiazole compound and the compound prepared by the preparation method. According to the method, the 1, 3, 4-oxadiazole compoun

Cyclodesulfurization of Substituted Thiosemicarbazides into 1,3,4-Oxadiazoles via Hydrazonoyl Chlorides

The reaction of thiosemicarbazides 1a-h with hydrazonoyl chlorides 2a-g at ambient temperature, in the presence of triethylamine yielded, in each case, two products. The structure of these compounds was confirmed as 1,3,4-oxadiazoles 14a-h and hydrazonoth

Hypervalent iodine(V) mediated mild and convenient synthesis of substituted 2-amino-1,3,4-oxadiazoles

A simple protocol for the synthesis of 2-amino-1,3,4-oxadiazoles starting from the corresponding acylhydrazides by cyclodesulfurization of intermediate acylthiosemicarbazides mediated by o-iodoxybenzoic acid in good yields has been described. The protocol

Synthesis of 2-amino-1,3,4-oxadiazoles from isoselenocyanates via cyclodeselenization

An efficient one-pot method to access 2-amino-1,3,4-oxadiazoles from isoselenocyanates and hydrazides or dihydrazides was developed via cyclodeselenization. Without any harsh reagents, various 2-amino-1,3,4- oxadiazoles were obtained in considerably high

Tetrazoles: LV. Perparation of 2-anilino-5-aryl(hetaryl)-1,3,4-oxadiazoles from 5-substituted tetrazoles under microwave activation

In reaction of 5-aryl(hetaryl)tetrazoles with phenyl isocyanate under the conditions of microwave activation the corresponding 2-anilino-5-aryl(hetaryl)- 1,3,4-oxadiazoles formed in high yields. The application of the microwave activation fourfold reduced

15N NMR study of substituted 2-(phenylamino)-5-phenyl-1,3,4- oxadiazoles

Substituted 2-(phenylamino)-5-phenyl-1,3,4-oxadiazoles were studied by 15N NMR spectroscopy. All signals were assigned on the basis of HMQC and HMBC experiments. Chemical shifts values were correlated with empirical Hammett parameters as well a

Fragmentation and skeletal rearrangements of 2-arylylamino-5-aryl-1,3,4- oxadiazoles and their noncovalent complexes with cobalt cation and cyclodextrin studied by mass spectrometry

Mass spectrometric fragmentation pathways of title compounds were studied by electron ionization (EI) and electrospray ionization (ESI) as methods of ion generation. To explain the observed complex skeletal rearrangements, tandem mass spectrometry, accurate mass measurement and isotope labeling (compounds containing one 13C atom in oxadiazole ring) were used. Loss of CO, N2 and H atoms under EI conditions led to the formation of 9,10-dihydroacridine-type ions, loss of NH3 under ESI conditions yielded the 4-phenylphthalazinone-type ions and the loss of HNCO under ESI conditions produced N-arylamino-benzonitrilium ions; however, this process can be affected by the electron-donor/electron-withdrawing properties of groups substituted at the phenyl rings. The ESI was used to study the complexes of the compounds with cobalt as well as with cyclodextrin. It was found that the compounds studied tend to form inclusion complexes with cyclodextrin of stoichiometry 1:1 and complexes of different stoichiometries with cobalt, although those of stoichiometry 6:1 and 4:1 are favored and the attachment of counter ion may stabilize the complexes 3:1 and 2:1. Copyright

Thermal Ring Transformation of 5-Aryl-2-carbazoyl-1,2,3,4-tetrazole Derivatives

Unstable 5-aryl-2-(3-benzylidene-2-phenylcarbazoyl)-1,2,3,4-tetrazoles 8 have been prepared.By thermal ring transformation, they gave 5-aryl-2-(2-benzylidene-1-phenylhydrazino)-1,3,4-oxadiazoles 9.Hydrazinolysis of 9 afforded 5-aryl-2-(1-phenylhydrazino)-