23767-54-6

Upstream product

• 110-91-8 morpholine 
• 41125-75-1 5-(4-methoxy)phenyl-1,3,4-oxadiazol-2(3H)-one 
• 23328-69-0 4-chloromorpholine 
• 829-35-6 2-(4-methoxyphenyl)-1,3,4-oxadiazole 
• 23766-26-9 5?(4?methoxyphenyl)?1,3,4?oxadiazole?2?thiol 
• 23767-33-1 2-(4-methoxy-phenyl)-5-methylsulfanyl-[1,3,4]oxadiazole 
• 23767-34-2 2-(p-methoxyphenyl)-5-(methanesulfonyl)-1,3,4-oxadiazole 

Relevant academic research and scientific papers

A new entry of amination reagents for heteroaromatic C-H bonds: Copper-catalyzed direct amination of azoles with chloroamines at room temperature

Chloroamine serves as an efficient amination reagent to the heteroaromatic C-H bond of azole under copper catalysis even at room temperature. This catalysis enables a rapid and concise construction of aminoazoles of great interest in biological and medicinal chemistry.

Efficient phosphonium-mediated synthesis of 2-amino-1,3,4-oxadiazoles

We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SnAr substitution using phosphonium reagents (e.g., BOP). This approach provides convenient access to N,