23779-64-8

Basic information

• Product Name: 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile
• CAS NO: 23779-64-8
• Molecular Formula: C₁₄H₅N₅
• Molecular Weight: 243.223
• Mol File: 23779-64-8.mol

Chemical Properties

• Boiling Point: 649.7°C at 760 mmHg
• Flash Point: 339.8°C
• Density: 1.41g/cm³
• Vapor Pressure: 9.19E-17mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile(23779-64-8)
• EPA Substance Registry System: 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile(23779-64-8)

Safety Data

• Hazardous Substances Data: 23779-64-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile is utilized as a building block in organic synthesis for constructing more complex molecules. Its unique structure allows for the creation of a variety of organic compounds that can have diverse applications in different fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile serves as a key intermediate in the synthesis of pharmaceutical compounds. Its incorporation into drug molecules can potentially enhance their therapeutic effects or improve their pharmacokinetic properties.
Used in Materials Science and Engineering:
3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile is used in materials science and engineering for the development of new materials with specific electronic or optical properties. Its unique molecular structure can contribute to the creation of materials with tailored characteristics for use in various high-tech applications.
Safety Considerations:
Due to the complex and potentially hazardous nature of 3-(4-cyanophenyl)cyclopropane-1,1,2,2-tetracarbonitrile, it is crucial that its handling and use are conducted with caution. Adherence to appropriate safety protocols is essential to mitigate any risks associated with its manipulation in laboratory or industrial settings.

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 109-77-3 malononitrile 
• 506-68-3 bromocyane 

Relevant articles and documents

Flash preparation of carbenoids: A different performance of cyanogen bromide

Cyanogen halides are known substances for the cyanating reaction. There are a few evidences for bromination reaction too. On the other hand carbenes are known as very important substances due to their remarkable reactions. Unfortunately carbenes at room temperature are very unstable and there is not a simple method for preparation of them. In most cases the isolation is not possible. We have reported a new reliable and fast preparation method of almost stable carbenoids. The mechanism of the formation has been discussed.

Solvent-free, one-pot synthesis of pentasubstituted cyclopropanes in the presence of BrCN and EtONa by milling

A solvent-free, one-pot process for the preparation of pentasubstituted 3-arylcyclopropane-1,1,2,2-tetracarbonitriles in the presence of solid sodium ethoxide by milling was achieved. The one-pot reaction of aromatic aldehydes and dialdehydes with malonon

A new, fast and easy strategy for one-pot synthesis of full substituted cyclopropanes: Direct transformation of aldehydes to 3-aryl-1,1,2,2- tetracyanocyclopropanes

A new, fast and easy method for one-pot reaction of aromatic aldehydes and dialdehydes with malononitrile and cyanogen bromide has been developed to afford full substituted 3-arylcyclopropane-1,1,2,2-tetracarbonitriles in excellent yields in very short time (about 5 seconds). The structures elucidations were characterized by IR, 1H NMR, 13C NMR, mass spectrometry and X-ray crystallography techniques. For these compounds the crystallographic data showed two structures in mirror image in solid case and one distinct structure in solution. The reaction mechanism was discussed.